1.A.10.1.14
Ionotropic receptor 25a, Ir25a. Not involved in salt sensing (Zhang et al. 2013). It resets the circadian clock in response to temperature (Chen et al. 2015). Monoacylglycerol acyltransferase maintains
ionotropic receptor expression for cool temperature sensing and
avoidance in Drosophila (Deng et al. 2025).
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| Accession Number: | E9NA96 |
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| Protein Name: | Ionotropic receptor 25a |
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| Length: | 947 |
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| Molecular Weight: | 108122.00 |
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| Species: | Drosophila melanogaster (Fruit fly) [7227] |
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| Number of TMSs: | 4 |
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| Substrate |
ion |
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1: MILMNPKTSK ILWLLGFLSL LSSFSLEIAA QTTQNINVLF INEVDNEPAA KAVEVVLTYL
61: KKNIRYGLSV QLDSIEANKS DAKVLLEAIC NKYATSIEKK QTPHLILDTT KSGIASETVK
121: SFTQALGLPT ISASYGQQGD LRQWRDLDEA KQKYLLQVMP PADIIPEAIR SIVIHMNITN
181: AAILYDDSFV MDHKYKSLLQ NIQTRHVITA IAKDGKRERE EQIEKLRNLD INNFFILGTL
241: QSIRMVLESV KPAYFERNFA WHAITQNEGE ISSQRDNATI MFMKPMAYTQ YRDRLGLLRT
301: TYNLNEEPQL SSAFYFDLAL RSFLTIKEML QSGAWPKDME YLNCDDFQGG NTPQRNLDLR
361: DYFTKITEPT SYGTFDLVTQ STQPFNGHSF MKFEMDINVL QIRGGSSVNS KSIGKWISGL
421: NSELIVKDEE QMKNLTADTV YRIFTVVQAP FIMRDETAPK GYKGYCIDLI NEIAAIVHFD
481: YTIQEVEDGK FGNMDENGQW NGIVKKLMDK QADIGLGSMS VMAEREIVID FTVPYYDLVG
541: ITIMMQRPSS PSSLFKFLTV LETNVWLCIL AAYFFTSFLM WIFDRWSPYS YQNNREKYKD
601: DEEKREFNLK ECLWFCMTSL TPQGGGEAPK NLSGRLVAAT WWLFGFIIIA SYTANLAAFL
661: TVSRLDTPVE SLDDLAKQYK ILYAPLNGSS AMTYFERMSN IEQMFYEIWK DLSLNDSLTA
721: VERSKLAVWD YPVSDKYTKM WQAMQEAKLP ATLDEAVARV RNSTAATGFA FLGDATDIRY
781: LQLTNCDLQV VGEEFSRKPY AIAVQQGSHL KDQFNNAILT LLNKRQLEKL KEKWWKNDEA
841: LAKCDKPEDQ SDGISIQNIG GVFIVIFVGI GMACITLVFE YWWYRYRKNP RIIDVAEANA
901: ERSNAADHPG KLVDGVILGH SGEKFEKSKA ALRPRFNQYP ATFKPRF