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1.A.10.1.7
The glutamate receptor 1.1 precursor (GLR1.1) (Ligand-gated channel 1.1, AtGLR1 (Kang and Turano, 2003)).  Clade 3 GLRs establish their critical role in generating electrical signals and increasing cytosolic Ca2+ in response to mechanical wounding, insect and pathogen attacks, and other environmental cues for systemic defense responses.  Riaz et al. 2025 review the roles of GLR in physiological processes, abiotic and biotic stresses, and strategies to enhance plant health and productivity.

Accession Number:Q9M8W7
Protein Name:Glutamate receptor 1.1 aka GLR1
Length:808
Molecular Weight:90509.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:4
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate ion

Cross database links:

RefSeq: NP_187061.1   
Entrez Gene ID: 819566   
Pfam: PF01094    PF00060    PF00497   
KEGG: ath:AT3G04110   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0030288 C:outer membrane-bounded periplasmic space
GO:0005261 F:cation channel activity
GO:0005234 F:extracellular-glutamate-gated ion channel a...
GO:0004970 F:ionotropic glutamate receptor activity
GO:0030003 P:cellular cation homeostasis
GO:0006811 P:ion transport

References (5)

[1] “Glutamate-receptor genes in plants.”  Lam H.-M.et.al.   9823891
[2] “Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.”  Salanoubat M.et.al.   11130713
[3] “Functional annotation of a full-length Arabidopsis cDNA collection.”  Seki M.et.al.   11910074
[4] “Phylogenetic and expression analysis of the glutamate-receptor-like gene family in Arabidopsis thaliana.”  Chiu J.C.et.al.   12082126
[5] “The putative glutamate receptor 1.1 (AtGLR1.1) functions as a regulator of carbon and nitrogen metabolism in Arabidopsis thaliana.”  Kang J.et.al.   12738881

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence 
1:	MEILFSISIL ALLFSGVVAA PSDDDVFEEV RVGLVVDLSS IQGKILETSF NLALSDFYGI 
61:	NNGYRTRVSV LVRDSQGDPI IALAAATDLL KNAKAEAIVG AQSLQEAKLL ATISEKAKVP 
121:	VISTFLPNTL SLKKYDNFIQ WTHDTTSEAK GITSLIQDFS CKSVVVIYED ADDWSESLQI 
181:	LVENFQDKGI YIARSASFAV SSSGENHMMN QLRKLKVSRA SVFVVHMSEI LVSRLFQCVE 
241:	KLGLMEEAFA WILTARTMNY LEHFAITRSM QGVIGFKSYI PVSEEVKNFT SRLRKRMGDD 
301:	TETEHSSVII GLRAHDIACI LANAVEKFSV SGKVEASSNV SADLLDTIRH SRFKGLSGDI 
361:	QISDNKFISE TFEIVNIGRE KQRRIGLWSG GSFSQRRQIV WPGRSRKIPR HRVLAEKGEK 
421:	KVLRVLVTAG NKVPHLVSVR PDPETGVNTV SGFCVEVFKT CIAPFNYELE FIPYRGNNDN 
481:	LAYLLSTQRD KYDAAVGDIT ITSNRSLYVD FTLPYTDIGI GILTVKKKSQ GMWTFFDPFE 
541:	KSLWLASGAF FVLTGIVVWL VERSVNPEFQ GSWGQQLSMM LWFGFSTIVF AHREKLQKMS 
601:	SRFLVIVWVF VVLILTSSYS ANLTSTKTIS RMQLNHQMVF GGSTTSMTAK LGSINAVEAY 
661:	AQLLRDGTLN HVINEIPYLS ILIGNYPNDF VMTDRVTNTN GFGFMFQKGS DLVPKVSREI 
721:	AKLRSLGMLK DMEKKWFQKL DSLNVHSNTE EVASTNDDDE ASKRFTFREL RGLFIIAGAA 
781:	HVLVLALHLF HTRQEVSRLC TKLQSFYK