1.A.17.5.6
Phosphate metabolism protein 7, Phm7, of 991 aas and 11 TMSs in a 3 + 4 + 2 + 2 TMS arrangement. It may act as an osmosensitive calcium-permeable cation channel. PHM6 and PHM7 genes are essential for phosphate surplus in the cells of Saccharomyces cerevisiae (Kulakovskaya et al. 2023). PHM6 is not homologous to PHM7 and is a small protein of 104 aas and 1 C-terminal TMS.
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| Accession Number: | Q12252 |
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| Protein Name: | Phosphate metabolism protein 7 |
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| Length: | 991 |
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| Molecular Weight: | 112546.00 |
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| Species: | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [559292] |
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| Number of TMSs: | 11 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
phosphate(3-) |
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1: MADSSSTSAF ISTLIIYGLT AVVFVWLFLL LRPKNRRVYE PRSLKDIQTI PEEERTEPVP
61: EGYFGWVEYL LSKPHSFLIQ HTSVDGYFLL RYIGIVGSLS FVGCLLLLPI LLPVNATNGN
121: NLQGFELLSF SNVTNKNRFY AHVFLSWIFF GLFTYVIYKE LYYYVVFRHA MQTTPLYDGL
181: LSSRTVIVTE LHKSIAQEGE MQMRFPKASN VAFAYDLSDL QELCKERAKN AAKYEAALNK
241: VLNKCVKMTR NKTQKQLDKL YNNGTKPKDD LETYVPHKKR PKHRLGKLPL CLGGKKVNTL
301: SYSSKRIGEL NEEIHEKQAD WASNDRQPAC FIQFETQLEA QRCYQSVEAI LGKKNFGKRL
361: IGYSPEDVNW GSMRLSSKER HSRRAVANTI MVLLIIFWAF PVAVVGIISN VNFLTDKVPF
421: LRFINNMPTF LMGVITGLLP TIALVVLMSL VPPFIVMLGK LSGCVTRQET DLYSQAWYYA
481: FAVIQIFLVV TATSSASSTV DSIIDRPRSA MTLLANNLPK ASNFYIMYFI LKGLTGPTWT
541: ILQAVNLLLS KVLGRVLDST PRQKWNRYNT LATPRMGIVY PGIEILVCIY ICYSIIAPIL
601: LFFSTVMLTL LYVAYLYNLN YVFGFSFDLK GRNYPRALFQ IFVGIYLSEV CLLGLFIMAK
661: TWGPLVLEVF WIVVTALAHI YMKRKFIPLF DAVPLSAIRH ARGEPGYSYP TSDLGLQEIK
721: DIADEMKGKY EQDNTHGILT PVTKDDLKKA NLIPDNDGSS ENGTPSNPFE SGSERASLSG
781: SNAESDSIKK LNDTVIKKSS TLSSSTKDNN ESTFVPEGEK FRKFHYSDVE ALRNKRPYDE
841: DDHSKHGPEG AVPVNADAGV IYSDPAAVMK EPQAFPPDVL ETNTWTRRIL QFFNPRRSYP
901: FDSVRMRFPL VFNTSIEYDE EYLSSAYTDP CVREKDPIVW CCKDPLGVSK QQIQEARSNG
961: LDVRDDFTRY DEKGKVIFTY NPPDYEPEAK K