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| Accession Number: | Q9Z182 |
| Protein Name: | SIC |
| Length: | 528 |
| Molecular Weight: | 61018.00 |
| Species: | Rattus norvegicus (Rat) [10116] |
| Number of TMSs: | 7 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | cation |
Cross database links:
Gene Ontology
GO:0005829
C:cytosol
GO:0030425
C:dendrite
GO:0043025
C:neuronal cell body
GO:0005886
C:plasma membrane
GO:0045202
C:synapse
GO:0005261
F:cation channel activity
GO:0017081
F:chloride channel regulator activity
GO:0005515
F:protein binding
GO:0006812
P:cation transport
GO:0071363
P:cellular response to growth factor stimulus
GO:0071502
P:cellular response to temperature stimulus
GO:0007204
P:elevation of cytosolic calcium ion concentr...
GO:0014047
P:glutamate secretion
GO:0001774
P:microglial cell activation
GO:0090212
P:negative regulation of establishment of blo...
GO:0043065
P:positive regulation of apoptosis
GO:0060454
P:positive regulation of gastric acid secretion
GO:0045429
P:positive regulation of nitric oxide biosynt...
GO:0043434
P:response to peptide hormone stimulus
GO:0009268
P:response to pH
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References (1)[1] “Cloning of a stretch-inhibitable nonselective cation channel.” Suzuki M.et.al. 10037722
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MYNEILILGA KLHPTLKLEE ITNRKGLTPL ALAASSGKIG VLAYILQREI HEPECRHLSR 61: KFTEWAYGAV HSSLYDLSCI DTCEKNSVLE VIAYSSSETP NRHDMLLVEP LNRLLQDKWD 121: RFVKRIFYFN FFVYCLYMII FTAAAYYRPV EGLPPYKLKN TVGDYFRVTG EILSVSGGVY 181: FFFRGIQYFL QRRPSLKSLF VDSYSEILFF VQSLFMLVSV VLYFSQRKEY VASMVFSLAM 241: GWTNMLYYTR GFQQMGIYAV MIEKMILRDL CRFMFVYLVF LFGFSTAVVT LIEDGKNNSL 301: PMESTPHKCR GSACKPGNSY NSLYSTCLEL FKFTIGMGDL EFTENYDFKA VFIILLLAYV 361: ILTYILLLNM LIALMGETVG QVSKESKHIW KLQWATTILD IERSFPVFLR KAFRSGEMVT 421: VGKSSDGTPD RRWCFRVDEV NWSHWNQNLG IINEDPGKSE IYQYYGFSHT MGRLRRDRWS 481: SVVPRVVELN KNSDTDEVVV PLDNLGNPNC DGHQQGYAPK WRAEDAPL