1.A.5.1.4
One of 10 receptors for the egg jelly ligands (REJ, REJ1 or PKD-REJ1) inducing the acrosome reaction in sea urchin eggs. Could be a regulator of sperm ion channels (Gunaratne et al. 2007).
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| Accession Number: | Q26627 |
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| Protein Name: | Sperm receptor for egg jelly |
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| Length: | 1450 |
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| Molecular Weight: | 158165.00 |
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| Species: | Strongylocentrotus purpuratus (Purple sea urchin) [7668] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Single-pass type I membrane protein2 |
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| Substrate |
ion |
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1: MSVFVILILF NAILNFKTVG PAAVSSKTVD CASAPCMNGG TCADGFNNFT CFCEEGFTGS
61: MCETEYGCFR PWFYGPAFGY CYLWERVDYN WTQARESCID QGRGAELASI HSAEENAFVY
121: AQIRRYAWIG LSDQVTEGVF DYADGTPVDY LSFPDKNKQS ETRDCVYVKH LRVDNWSLLD
181: CRANKTSICK STTTFSATDG CATGWVHNPA TGYCYFYEER GGMWSKGREF CLDAGADLAS
241: IHSAEENAFI FDMLTEFVWL GLNDLETEGV YTNFSDGTPA DFDNFPADNY QNEDHDCVSI
301: RHLEKTDRYW FFLGCDDTVT SICKRPHEVV ATQAPPYLFT TTDVPATTTT IPTTTTTISA
361: TTRTIDAMIL IELLLFPNNV SSIDNIFRVN NTILVTASVL GSFQALSSQI LWSITNHLSG
421: DSVQYTVYSE DAVLVRFTTV SIFTIKATAV GNSHNLTATA NATVKHVCIS SLTTSVKEHC
481: DAPHPAVYLR AFDIHISTHM ELNGKCIDPM TPDFKWRIFT STEADDVVTA FEKITHTRQV
541: MIPRGTLPYG IYSLNLNAKT RLKTSGEVTG EKEIISWLEI QPPPLVAVIK GGASRSHGVS
601: SNLIVDGSNS YDPDVPPGSS SNVTFLWYCV VVDPDVMYSS LDEAIQNTDN ACFEDEGIMM
661: NSTSSMIEVI ANKLNANVTM NFWLNISKEG QISGLTQQRI HLTLGLLPEI EISCISNCNM
721: YIFTAERLVL HASCTNCDSE NEDVSFRWSL ESNHTSVIGD LSSQTTTGLD QPYLVLKPLT
781: FDSISEMGSI ILRVTGSQSD SDGYAEFSVD LPHNAPPALG SCVVTPDEGY ALQTDFTVTC
841: SNFTDVDEPL TYQIILFSHV DVVDWMFVGR GEGFQLYEGS APIKDGLYLP VGVGTDDHDI
901: LLQVNVRDCN MASTSVYISA TVHPPTLDAV GMNLVQELLD MALLVETNVN ALLAVGDPGQ
961: AAQLISALGS ILNSIGDEDD SEEGRETRSE IRSFLVDCVA AIPVESMTSL KQSSAALAVV
1021: THNKQEISTH VQMLAASTLS EMTSFVKSKS GSYTQAQENI ESAGTILVEG LSNILSAAKE
1081: TERLLSDDTS QEREDHKNLI EVAVSTINDI QDAIVAGKIP SEAATIITSP ALSIAVGSIS
1141: RDELAEATFG GPEDLGSFRM PSQDVLNQAM EHALGTTVSM KMSAMKWNPF SWPGAGGESI
1201: KSSIVGIQLE ADQMLEFHDL TADIDVYLPM RETLSADPVS VHITKTSSDS VLIDHSSLPV
1261: DGALHLTVIA ENEPMVALSI CTARISITES SCVGTDTPLG VSNEDPDTDA NFTWTVPLVD
1321: LKAADGIMIR LYDSEDQPGY ENDNITLSVF MHTLQCNFWN EDQQEWDSTG CKVGPLSKPS
1381: TTHCLCNHLT GFFGSSILVP PNHAQPVIGG HKLTGVDFLI CVLIGYGIYC VALVIRVVGC
1441: SFAIRVHKVL