1.A.5.4.1
The algal PDK2 cation channel in Chlamydomonas reinhardii, involved in coupling flagellar adhesion at the beginning of mating to the increase in flagellar calcium required for subsequent steps in mating (Huang et al., 2007). (Residues 1278-1346 (the PKD domain) are 25% identical, 54% similar to residues 107-176 in CcaA (TC# 1.A.1.14.2))
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| Accession Number: | A9LE42 |
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| Protein Name: | PDK2 |
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| Length: | 1626 |
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| Molecular Weight: | 181133.00 |
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| Species: | Chlamydomonas reinhardtii [3055] |
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| Number of TMSs: | 8 |
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| Location1 / Topology2 / Orientation3: |
Mitochondrion membrane1 / Multi-pass membrane protein2 |
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| Substrate |
cation |
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| Pfam: |
PF08016
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[1] “Function and dynamics of PKD2 in Chlamydomonas reinhardtii flagella.” Huang K. et.al. 17984324
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1: MAPLQAEDPQ KYRLEEGDGT THAQRIVREL YQRYERQLQR WKDYRNLFIF LCFVALFLGV
61: LYEQRNAGIS YQVHSTIESV AAPSDNIMQD TDAVYSWLNG LLTEVWKDPV CGDGLCEAPF
121: EFASYSRFGC RADCGKLSEV QNLTKIQIDI YYDFSHPVGS IPASDLMQQA SWNLCPLATA
181: YSSDCYFDAD KEFDRLSGVQ NFVLDDAPDG DWNLVVRRDI FNKIRGAVRD TTLVYASAFY
241: YKIYVAAAAA RAEQAFEISL LNQAINITSQ DFWTYANSVI MAGYPNATEY DAAVGWVKNA
301: TCFCDSVAND TVASGTPFTP EALMLYLNQS VSATDPNAPF SYTLTQYKND PYYCASGPFD
361: PREWRGRNVT VNSTAVNATA NSTASSGNVT WTKELVTINM ANQTALRDWC VGGLNLSIAW
421: RTNMTNTVQR LLIDRRLGDQ RTTGKIAQRN NVNDRMLAFI RANRPELVAP VFNAPRGTVA
481: LQDPINARLE YLYPLYVDGV KYSTEPQRAA LNMTRRIVYN TTVHLLSLRP RAAARIAEVQ
541: EQIADVRAIA LPTPITSYQN YTFPNATVGD VYDAFINAGA TSFTVPAPTN SSLGAFQVSY
601: NLVEWLGNTT AYMRCDLADR GAEYEGECVA MNNTCIATTN DTVPYNCTDL TNNGATITGN
661: LSNPDYRMRC ETPCDRRFDC NTICECYGTC AATEYCECDA CIQLNVNAAA DTQFVDIRSI
721: VQDQAAASAS IASIGLSGTV NRRASRRLLT TNEEIAAQLS NVLTQVGTVS TQQGSIATQM
781: ATLKAQVDRA NQLAEARAND NRLIDLINAG RADIQAGQAR VEAKLDEIIG KQNQALAAAE
841: DAAKALSAIQ GLAERQVAAQ RALETAVTNQ LSAIKTATYQ SIITLTQALA LWKRARRDKA
901: LTLKAAKLAN VPCTSDPVST NTFTLDNGNI VDTTTSRERN VGLTNRVIGG LLLHQTRTNE
961: TLCPESKFDK IQKTCTGPQT VASFGVDPIF KRGTTLYNPD YDDVNGTKVL DFYNCSVLSS
1021: PTYNVSFLNQ TVNPAPYCAE LYNPQELPYA FHFFPLSGKD DGFPVWFDIN LSQDGAQTWF
1081: TYLQEGLYLD QNTRTMTAEM VTYNAPLRIF SYFYIKFYFS DGGSIKVTYR LNTARVELQN
1141: SYEDDVRFGF EIILSIWISL LLLINFWDIG NCQKTKGNFL KYFLSGWNWV EFCSNGLLFS
1201: CMVMWWVISS KYASKFEIPI RRDVYAGLSA EANFLALQSN GAWLNEANND FEELKQLVDM
1261: FNWYFALNGI NILLLIARVL KLMDFQPRLG VVTRSLWLAG PDLCHFAIVA GMVFVGYAMM
1321: GHLIFGNAIP AFATFGDAIN TCFEILLGNI DVNSDLRALG GLQSVAGALW FWSYELLVYM
1381: VLLNFLLAII VDAFSEVKEK THETVGIHTE LFQLMRDKWR SLLGSFSPNY ISDAKLGDLL
1441: RQWAGEGDDK DDSPEVREEK RKLLTILNED MDEETLREVF EECLRDAPAA DPKAKQGNVL
1501: ARLFKRNVGA GDTDATKKEI EQAAHYIVER FGAVPDDYDE DEDDDQEQLQ AAPQQAIMGG
1561: GGMPAAPGAR EAVLEKERDQ LAQALERLAE VQRELAEGQR NLMSGQKQLA EQQSKLVQLM
1621: NETPPQ