Search TCDB: (?)
TCDB is operated by the Saier Lab Bioinformatics Group
« See all members of the family


1.A.56.2.2
High affinity copper transporter, Ctr1p (Marvin et al., 2004) of 251 aas with 4 putative TMSs, one N-terminal, a second at residue 100, and two more C-terminal. Chlorhexidine digluconate (CHG) is a broad-spectrum antimicrobial agent widely used in dental practice and has been recommended to treat oral candidiasis. It targets Ctr1p in C. albicans (Jiang et al. 2023).

Accession Number:Q9P871
Protein Name:Ctr1p
Length:251
Molecular Weight:27803.00
Species:Candida albicans (Yeast) [5476]
Number of TMSs:2
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate copper(1+)

Cross database links:

Pfam: PF04145   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0005375 F:copper ion transmembrane transporter activity
GO:0006825 P:copper ion transport

References (1)

[1] “The Candida albicans CTR1 gene encodes a functional copper transporter.”  Marvin M.E.et.al.   12777486

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
Window Size: Angle:  
FASTA formatted sequence 
1:	MEFLKRHEGH MHMSDSATSM AMSATSAVMD MASATMSMAM SSSTSSSSGM AMEGMDHGSS 
61:	HMAMNMWLTA SFKDYPVVFK DLRASTKAQA FGIFVLLFFV AFLARMLEFV RNYLEEIVWK 
121:	NNNYAEVEQG ISQHSANLQS PPVKSCCDDN AKEVVSDESI DKQNSPQHEE TTKARGTGKS 
181:	LSLASTISRD IIRLALCIIP DLFAYSLMLA AMTYTLTYFF AVVIGSGVGR FVAERLMEHY 
241:	RIKRGPPKNC C