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| Accession Number: | P12397 |
| Protein Name: | Chain F |
| Length: | 708 |
| Molecular Weight: | 76146.00 |
| Species: | Reovirus type 2 (strain D5/Jones) (T2J) (Mammalian orthoreovirus 2) [10885] |
| Location1 / Topology2 / Orientation3: | Virion1 / Lipid-anchor2 |
| Substrate | lithium(1+), sodium(1+), potassium(1+), rubidium(1+), caesium(1+) |
Cross database links:
| RefSeq: | NP_694625.1 |
|---|---|
| Entrez Gene ID: | 956464 |
| Pfam: | PF05993 |
Gene Ontology
GO:0044165
C:host cell endoplasmic reticulum
GO:0033650
C:host cell mitochondrion
GO:0020002
C:host cell plasma membrane
GO:0016020
C:membrane
GO:0019028
C:viral capsid
GO:0043498
F:cell surface binding
GO:0005515
F:protein binding
GO:0006915
P:apoptosis
GO:0009405
P:pathogenesis
GO:0019063
P:virion penetration into host cell
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References (2)[1] “Evolution of reovirus genes: a comparison of serotype 1, 2, and 3 M2 genome segments, which encode the major structural capsid protein mu 1C.” Wiener J.R.et.al. 3354208 [2] “A carboxy-terminal fragment of protein mu 1/mu 1C is present in infectious subvirion particles of mammalian reoviruses and is proposed to have a role in penetration.” Nibert M.L.et.al. 1328674
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MGNASSIVQT INVTGDGNVF KPSAETSSTA VPSLSLSPGM LNPGGVPWIA IGDETSVTSP 61: GALRRMTSKD IPETAIINTD NSSGAVPSES ALVPYNDEPL VVVTEHAIAN FTKAEMALEF 121: NREFLDKLRV LSVSPKYSDL LTYVDCYVGV SARQALNNFQ KQVPVITPTR QTMYVDSIQA 181: ALKALEKWEI DLRVAQTLLP TNVPIGEVSC PMQSVVKLLD DQLPDDSLIR RYPKEAAVAL 241: AKRNGGIQWM DVSEGTVMNE AVNAVAASAL APSASAPPLE EKSKLTEQAM DLVTAAEPEI 301: IASLVPVPAP VFAIPPKPAD YNVRTLKIDE ATWLRMIPKT MNTPFQIQVT DNTGTSWHMN 361: LRGGTRVVNL DQIAPMRFVL DLGGKSYKET SWDPNGKKVG FIVFQSKIPF ELWTAASQIG 421: QATVVNYVQL YAEDSSFTAQ SIIATTSLAY NYEPEQLNKT DPEMNYYLLA AFIDSAAIST 481: SNMTQPDVWD ALLTMSPLSA GEVTVKGAVV SEVIPADLVG SYTPESLNAS LPNDAARCMI 541: DRASKIAEAI KIDDDAGPDE YSPNSVPIQG QLAISQLETG YGVRIFNPKG ILSKIASRAM 601: QAFIGDPSTI ITQAAPVLSD KNNWIALAQG VKTSLRTKSL SAGVKTAVSK LSSSESIQSW 661: TQGFLDKVST HFPAPKPDCP QSGDSGDGSA RRLKRDSYAG VVKRGYTR