1.A.75.1.3
Piezo mechanosensitive ion channel of 2760 aas and ~38 TMSs in a 4 x 9 + 2 TMS arrangement (Kim et al., 2012)
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| Accession Number: | Q9VLS3 |
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| Protein Name: | CG8486, isoform D |
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| Length: | 2760 |
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| Molecular Weight: | 312529.00 |
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| Species: | Drosophila melanogaster (Fruit fly) [7227] |
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| Number of TMSs: | 39 |
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| Substrate |
ion |
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| Entrez Gene ID: |
34112
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| Pfam: |
PF12166
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| KEGG: |
dme:Dmel_CG8486
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[1] “Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.” Misra S. et.al. 12537572
[2] “The genome sequence of Drosophila melanogaster.” Adams M.D. et.al. 10731132
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1: MVFSYACMVL QRIVVPAVLV LAALMRPVGI SFVYLLMFFV SPFVPLATRR NFKGSVTAFF
61: IILLTLSTLV LLGHITLQIL AVSLTLPIYN CSFSERLLRH IGFVSFIDLQ PFAIIEWLVP
121: EVLVFATSLG SYLTVKRVAS QPVGAEQLEN GEVVDGQAEN AQTSSQPSAA DANGGDVQQA
181: TVTTPLQQQQ QQLRKRVSMI SQHIHFEGLV KISPLFCLAT LFFAAVLRPS VPGGFYFLIF
241: LLSGTYWATC QTLQRGFALL LRCVMVVLVL HSLSIVSYQT PWMQSHLNHT TLTARLIGLE
301: PLIESYCSPD IRVFLYNNKL SLDSYLNPFA LFFAYFALAL TTKHLIKPRL EPKPATALGQ
361: QLDCNSSSIN NTTGNKVNRQ LSLLTSQTSR GRRDGSNPGG GGTTITTTTT TTSTTAIRNQ
421: RLSLVRQSTR KARTPQPLES GSSVAPSVTQ RGNDMQLESM EQRSEQENTT TSILDQISYG
481: FVSVGGFIYQ NSYIFTNILM MAWSIVYHSW LTFVLLLSAN VLWMIPNQRK AMMRSSPFIV
541: LYAEALLIAQ YIYGMDLNNE ELPTSVPTAG INLQQIGFER PIENQMRPCV PLIVKTAFVL
601: MFWVTSRQFF KEKRDRRRDS TLADFIAPLQ ITVGSAGSSY LINDGKKTSK FLKKAGDVIK
661: NLLVRLWIWL LVLVIFLCAI TGENMTGFRI CYMALFLFFL LVFQSSSKAW VKIMYGFWLF
721: LIFYAMSILI LIYTYQFDKF DTYWSDYLNV SATLQKDIGL KRYQTKDLFL HLVSPTIIVI
781: LTVIQVHYFH KRFIASLQQQ PLAGGSAQQK PTETTALEPA PSKRRGSAGS LRKSQGPSAE
841: AAPGATTDFE TSVRDLVRIS FRKIKNKSEY IFKNFKDVFW RFLELHIMKA VYIAAFVCSV
901: SEVCVLHIIF VGFCVLGATS RKAVQVVISR LISFIVTVIV LSKMIYQIEY LSHSQHNVVC
961: SDNRTANNAE WIGLTKADKV TGGLMSLLRT YIIYMVIVTM HAVISLRQLQ MRVKIGALNA
1021: PPTKLLFPNI IRADAEKDLV GLVKYLLNFG FYKFGIEISL IALVSTITYR QDIVAVVYAL
1081: WLVVLLLLRR SQCAKIWGVF QAFFAISILT QYIVLVGLPP SSCLVFPWDE GPFGEGIQRW
1141: AMLPGALHFN HVPKLIFDFI VLVILNRQKS IFCIEQRYAS NDDYPGGSNR SVIADIAQLG
1201: RVPFDNPTHD FCSYIRNYSD ILKNGVLCGF YWFTLAVVFL AGTNIADLLA LGYLIGAFIF
1261: LWQGSDFYLR PIHTIIFRWK WLLAFNVANI LIKTSFQMAG CLFMTQLTKD CCWLVHMLGI
1321: TCTSNVLTEQ IMLPEEAELA LKPGECPKIT HQVVLLWDTI CFAFIIFQLR IFKSHYFCHI
1381: ITDTKANNIL ASRGADIIES LRHKQIAHRH DHEKQVLHKI KRKMERIRAT QQKMLRPLDK
1441: QTHFDEHGYP LPAPTVRRRK EIKLHPHATR AGDYYMFEEM DDKFELDLIH DEIDFLEEEN
1501: ITESEMKMQR RKTLYDVWKD LNDAEYRRHF YMRERSYASE PGSRILLKLD DEKEKIGPDL
1561: GLASDHDEDD DTIECDLGMR TSTLSEPLDF GRRSQTLLEV KSKDAPTGEF PSTSKGISKE
1621: RDAATASSSA SPAPTRDVGD LPVIPPPSTG LGREQTSKET SDSKSKMEVD SGEVTAKDSD
1681: EDFDTNPIIR LLEGFLVTLT IRLNRFSRNY RFVNRILAGE KKTLKESSSL NRLGLSSAAA
1741: MFHFLKSNLE SDESEPPASS STPRRVVIAP PNATEHSDPT STTLNTNTTT TPLSPPEPLQ
1801: PLQPLQPNTT STPQQQHQHI RAAEEIIELP VDTVDGVAHR KQSINSSPPA KGTMLSRKSD
1861: CGLPEIRIKA PSIERGAHYY HNHHSGGGSG SLSKHWSYEQ VDSAGEFNLE EENFAQRDHH
1921: IIVEVLISSW YALLANTDLI CYIVVFINQV VNASLISLPL PIMVFLWGTL SLPRPTKTFW
1981: VTLIAYTQAI VLIKCIFQFK LIWSNYHQLP NQPLTPAKIF GVENKAHYAI YDLILLLVLF
2041: LHRYLLKSQG LWKSGYKDTD NQFTKPTASI DERDDSDNLS QPDSRQLNDD AAQKLSLQVS
2101: QASLPGSPEF SKTGINQLER TKYTSSLYKF FFSLVHKSRL ATDVYALMFL CDFVNFFVLL
2161: FGFTAFGTQQ TESDEGVQTY LAENKVPIPF LIMLLVQFLL IVIDRALYLR KALVNKIIFH
2221: FFSVIGIHIW MFFVVPAVTE RTFNSLAPPI IFYVIKCFYM LLSSYQIKSG YPKRILGNFF
2281: TKGFSMVNMI AFKVYMQIPF LYELRTILDW VCIDSTMTIF DWLKMEDIFS NIYLIRCTRQ
2341: SETDFPAMRA QKKASLSKLI MGGTIVLLIV ICIWGPLCLF ALGNAVGTSN VPFHVSLSIR
2401: IGPYDPIYTT NNYDSIFEIN PEMYSQMTNA YIKEKQALTF IAGYDATDVA AVRLAGNSPS
2461: LWNIAPPDRQ RLLNDLRNNH TLKARFSYSL TRKAPAKGLK ENVGDEHAIS LDESFEGRAA
2521: LIHMLSETHD VEPIYSNGTT NGTTPEVEEV VVIPGMIPKF IKVLNSGDAA VVSVLSPKHY
2581: DYRPLVIKMH RDNETNGLWW EIRDYCNDTF YNETLSKFAY SNCTSGIVMY TFNDKKFPST
2641: FSFLTAGGII GLYTTFVLLA SRFMKSFIGG QNRKIMFEDL PYVDRVLQLC LDIYLVREAL
2701: EFALEEDLFA KLLFLYRSPE TLIKWTRPKE EYVDDDGDTD SIPSRMSVRR PEQLQPQQPQ