1.A.75.1.4
Piezo protein homolog of 2462 aas and possibly 42 TMSs in an approximately 4 x 10 + 2 TMS arrangement. This piezo-like protein suppresses systemic movement of plant viruses in Arabidopsis thaliana (Zhang et al. 2019). It plays a role in root cap mechanotransduction (Fang et al. 2021) and modulates vacuole morphology during tip growth (Radin et al. 2021). Arabidopsis PIEZO1 localizes to the tonoplast and is required for vacuole tubulation in the tips of pollen tubes.
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| Accession Number: | F4IN58 |
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| Protein Name: | Uncharacterized protein |
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| Length: | 2462 |
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| Molecular Weight: | 282275.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 30 |
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| Substrate |
cation |
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1: MASFLVGFLL PSLLLAAALI NWSVISFLDL IAFLLVHYIA PEIGYRFQRR HWLLWPIFIF
61: SFAVFLAQVV YLVIWAALGQ DWDTPDTGWM RVIGFMILKS WRNPTVMYFL ALQLLTSLVA
121: LADIYSSRFG FARWRDTWWS HFSGIFEHLG SHLRVASCLL LPAVQLAVGI CNPSWVSLPF
181: FIGSCAGLVD WSLTSNVSGL FRWWRVLYIY AGFNIVLLYL YQLPINFSDM IRWIASFIGL
241: FRISLETEGP DICSGLFLVL FYIMLSYVRS DLEDMDFIMS TSENNLAERL LPPKYSFFIR
301: ESRAGVRHTN VLLRGAVFKT FSINFFTYGF PVSLFALSFW SFHFASLCAF GLLAYVGYII
361: YAFPSLFQLH RLNGLLLVFI LLWAVSTYIF NVAFSFLNTK VGKFGLGMLV ALGNLVNNSV
421: FLYLSEESSR SSNERSYVEA DEETKVLVVA TIAWGLRKCS RAIMLALIFL IAMKPGFFHA
481: VYVIFFLMYL LSHNINRKIR KSLILLCEVH FALLYILEID LVSNSLKQEG SASREVLFQL
541: GLLRSESSWD FLEIALLACF CAIHNHGFEV LFSFSAIVRH TPSPPIGFSI LKAGLNKSVL
601: LSVYSSPSSS YSQDNTTYER HIASFLSAIG QKFLSMYRSC GTYIAFITIL ISVYLVKPNY
661: VSFGYIFLLL LWITGRQLFE ETKRRLWFPL KAYAVLVFMF IYCLSSFVSL QLWLSGFIDL
721: YFYLGYNSKA PLLDNVWESL AVLIVMQLYS YERRQSGHYI PGQSSLLHPG VFGFFERFLA
781: WHGQKILFAA LFYASLSPIS VFGFVYLLGL VICTTFPKSS SIPSKSFLIY TGFLVSAEYL
841: FQLWGMQAQM FPGQKYAELS FYLGLRVYEP GFWGIESGLR GKVLVVAACT LQYNVFRWLE
901: RTSGLTVIKG KYEEPCPLFV SAEDTTASVS SSNGENPSST DHASISMKQG EATSNSWPFF
961: SPRGNQGAGF LHPKTGGSES GSSRKFSFGH FWGSIKESHR WNRRRILALK KERFETQKNL
1021: LKIYLKFWIE NMFNLYGLEI NMIALLLASF ALLNAISMVY IALLAACVLL RRRVIQKLWP
1081: VVVFLFASIL AIEYVATWNS FLPSDQAPSE TSVHCHDCWS IAALYFKFCR ECWLGVRVDD
1141: PRTLISYFVV FMLACFKLRA DHISSFSESS TYHQMKSQRK NSFVWRDLSF ETKSMWTVLD
1201: YLRLYCYVHL LDVVLILILI TGTLEYDILH LGYLAFALVF ARMRLEILKK KNKIFRFLRV
1261: YNFVLIIFSL AYQSPFVGNF NDGKCETVDY IYEVIGFYKY DYGFRITARS ALVEIIIFML
1321: VSLQSYMFSS QEFDYVSRYL EAEQIGAIVR EQEKKAARKT EQLQQIREAE EKKRQRNLQV
1381: EKMKSEMLNL RVQLHRMNSD SNFGVASPRT EGLRRRKSPY LIPDSGAASP EIDGVVHRKE
1441: EQPIDEDSQY PFEAHEFPVS TTPEALDSPE YSFGASPCEI TEVQQDLDVM SMERERKQKS
1501: EGKENPLISA VQLIGDGVSQ VQFIGNQAVN NLVNFLNISP ENSDTNEQSS VDDEVYDEME
1561: SQKRKHTPFE RSTSLQSDRS SDGTSFQIGR IFRHIWSRMQ SNNDIVCYCC FIIAFLWNFS
1621: LLSMVYLAAL FLYALCVHTG PTHIFWVIML MYTEIYILLQ YLYQIIIQHC GLSIDAPLLH
1681: ELGFPTQRIK SSFVVSSLPL FLIYIFTLIQ SSITVKDGDW VPSADFTSRR NARGSQKDLT
1741: RIRLSQRILD VFKKLRDSAK LVIRSIYRYW ISLTRGAESP PYFVQVTMDV HMWPEDGIQP
1801: ERVECRMNQL LRLVHNERCE KGNPDLCPYS SRVHVQSIER STETPNEALV VLEVEYASPT
1861: NGCSSAEWYK SLTPASDVAK EIRKAQHSGL GEGTGFPYPI LSVIGGGKRD TDLYAYIFGA
1921: DLIVFFLVAI FYQSVIKNKS EFIDVYQLED QFPFDFVIIL MVIFFLIVVD RVIYLCSFAT
1981: GKVVYYLFSL ILFTYAVTEY AWSIYPTQQH AAGLALRIIF LAKAMSLALQ AIQIRYGLPH
2041: KSTLYRQFLT SEVSRINYYG YRLYRALPFL YELRCVLDWS CTATSLTMYD WLKLEDVNAS
2101: LYLVKCDTVL NRATHKHGEK QTKMTKCCNG ICLFFILLCV IWAPMLMYSS GNPTNIANPI
2161: KDASVQIDLK TVGGKLTLYQ TTLCERISGD NIDLGLDLGS QSFLPTYNKN DIQLICCQAD
2221: ASVLWLVPDT VVTRFIQSLD WDTDMDITFT WVLNRDRPKG KETVKYERSV DPLDLPKRSD
2281: IQMVLNGSMD GFRVHNLYPK FFRVTGSGDV RSFEDQTDEV SADILINHAN FKWWWSFHNL
2341: KASENISACE GMDGPVAIIM SEETPPQGFL GDTLSKFSIW GLYITFVLAV GRFIRLQCSD
2401: LRMRIPYENL PSCDRLIAIC EDLYAARAEG ELGVEEVLYW TLVKIYRSPH MLLEYTKLDY
2461: DA