1.A.75.1.7
Piezo homologue of 2382 aas and ~ 38 TMSs in a 4 x 9 + 2 TMS arrangement.
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| Accession Number: | F1KPQ0 |
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| Protein Name: | Piezo-type mechanosensitive ion channel component |
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| Length: | 2382 |
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| Molecular Weight: | 270116.00 |
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| Species: | Ascaris suum (Pig roundworm) [6253] |
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| Number of TMSs: | 37 |
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| Location1 / Topology2 / Orientation3: |
Membrane1 / Multi-pass membrane protein2 |
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| Substrate |
cation |
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1: MVSVWAKNFV REAVLVPALL CAALIRPSLV SVVYVILALL GPLFPSIKAS CAVPSSTKAH
61: VILVLLVSLL AAISQFTYQI YESITGPDID DYTAACNSSD FDFWMRQIGL IRVKPDAGLD
121: AVRVVAPEVL ALLSSALTAV ICLAFAHHPP SSANTAPHSV YVQPVRPMPS PLATPSKSVK
181: FVAACVVALK RLGDVAIILF VGLVGVIQPS ILNAVYFLAF LFVATWWASY TPLHRRVYNA
241: IKRLLIFYTA LHFLAVYIYQ IPFVQYALPS GSFPARVIGF VAILRTECPH WWTLSLISAD
301: YWTAFANALL LLLLYYSLVF QYKCSRYGLL RSLTYVGSTE SSVHEENMAM SQYSASHSAE
361: RESNEAQRVK NGGIRRARDN TLLVTDDDEE PLESVPLQRI TSAVIDRQKI ASIFRSANGT
421: ESVPSQGLIS ILSFCLYHGY MLGLLAMMAW GLMYHSVFGL VFLMAAFIFW VFKDTRSVSF
481: AISPLILTYA EFLLMAQYVC SMDITNELPK SDFLEMIGFV LATDRISAFV TLLVKGILCL
541: PLLVLLRLHL REKFYNSLSE RDRRKRLTYG TFSTSSRQPT SSHNAEQDPS VTLNQSRGAQ
601: AVSCVSTALS KYWIFVVSLV LLLVSIQSPP LFYTLGYFIF FAVLLTLLQV SLGCLRRTLF
661: LYWTLIVLYS SVVLLAVYCF QFPGFPKHWQ EITGLDKEWT RDIGLINYKE EGDSSVLFIR
721: LIAPISFFFV AMLQLKFFHD PWCRIVAPPG RSAVVGDGPV DAQEPTSRYA KAKAFFEAAT
781: EVLWRIAEVH VTKLVLLVLI IVAVNDVCEL NVMIPVFISI AVCLPSISRL LSALLCIYLS
841: LFALARMLYQ MHFISENATV YVYADRSSCN LSGITMVPTT EWLGFHKVFD IGSYIAGLIV
901: SMVVLALQAV ILYRQRHARM LRGEPTPPRG VIFANSGMAV WDTSFVDMLK FFLDYGFYKF
961: GLEISMTMMV VVAWVRMDLI GTLTLLWLFV FACMSRPGCR RLWPLFLLYL AILFPLQYQL
1021: YVGLPPELCI DYPWSHWLSN PIQNDNLILW LDLASYRIHL NPYNTIADFF LLVMVACQEC
1081: AFRAENSNHP ADDNKSVYST GDYKLAVNNP RYDFIAHQRS LVDFLKVAVF NYGHWATLIM
1141: VLVAGLGGVS LFALGYIVLA FSMLWRGNNL YVMNKYQLTL KRWKLLLLYT VFTMFWKVAL
1201: QVVGCAFIHL LRDANLCYLR QLFSIVCVSK DSDRDDNYYF PGQLEFDNTC TVQKSETQIG
1261: FDTFAFAFLI FQMRILHSWY FQHCMLDYRS EAVLMNRGAV LTNQLIAKEM KEQNLQQSRK
1321: FDEIKQRTAT IRKRYEEQQH YGAAGAFTPQ TYGQAKRAGD YYMFEYDPNR DELVKPIESF
1381: VPEVTPGAEK FDKLDPAQLL HTAVQRDLDL SGTLNAVETA EKIEDEEKRM IEAVSLHRDV
1441: PPAPLREDET PEHAEDEGDS ERDEQEAHEG IGSKILVGLR FAWKLVLSAL DMTAAFLNRR
1501: SRDHRYVAFV LTREKENLKQ SLREQLTDVT QPLVGVREEF ERKNLHCVSS EGDIERLETE
1561: ALDAWQQRDV LARLITACGH CIAAHTDILC YLFAIIDHAR SAGLLSMPLP LLVFFWGSLA
1621: SPRPAKMFWI VMIGYTQLIV VIKFICQFGF FPWNETSAAI KLANSPNYLP GILGVRKEAY
1681: YAFWDIVLLV ALFFHRYMLR RMGLWNEANV SDTFTGETSI EEDSDALAYK TTAGSQENTA
1741: ETEAVVGDNV ATNVEVEGVQ KKRGPVANFF HQLFYPKFRY IRDLYPFMFL LDVLCFFVVS
1801: FGYSAFGYGG TGSVVKDISS NRVPITFVVM LIVISLMIVV DRALYLRKAV LCKLIYQFIT
1861: VIFLHIWIFF VLPAITYQAA WLNKTAQFLY CVKCVYLLIS AWQIRNGYPA LCIGNLITHA
1921: YGLANMIFFK AFMAIPFIFE VRTAIDWTWT DTSMPLFDYF NMENFYATIY NLKCARTFEQ
1981: NFPAPRGVPK GIVVKYLMGI PMIVILILVI WLPLLAFSLL NRIGMVLIPD NVQMTISVEG
2041: YPPLYSMEAQ GIELAMLSQN EYDFIQNAFA ERFNSSDQNS ILRARQAVAF INEYTLEDTL
2101: KVRFRPESEL FWSISSDSLT AMKYELQEGT KTINAIVKLQ FVRPRSGDSK EPTVHSSTIT
2161: IPLRKGSQTR DSLIALLNGT DPSINMTLKN SLPPYVIVPN EGEVKAPPTL LAVMHNSALF
2221: TRVDEVYSDL AMKLKPNNNL TDMLWSVELE QDNATNSLTL PLEHVRYGSD HSLEYVQMVA
2281: FVDRVFPSFV TKYVQGGIIA MYIAVVLLVG RLIRGIVTNA PLDVIISEIP NPDYLLKICL
2341: DIYLVREAKD FVLEQDLFAK LIFLFRSPAT LIKWTRFKVK SE