1.A.8.9.11 Aqp1 of 304 aas and 6 TMSs; the most abundant transmembrane protein in the tegument of Schistosoma mansoni.
This protein is expressed in all developmental stages and seems to be essential in parasite survival
since it plays a crucial role in osmoregulation, nutrient transport and drug uptake (Figueiredo et al. 2014).
|
Accession Number: | C4PYI6 |
Protein Name: | Aquaporin |
Length: | 304 |
Molecular Weight: | 32892.00 |
Species: | Schistosoma mansoni (Blood fluke) [6183] |
Number of TMSs: | 6 |
Substrate |
water |
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1: MVSCSEKYAH KQHIVADRLR LTSSPLVRAC LGEFMGSIIL MIFGSGVLAQ VILGDHGKHA
61: HGTFISVSLG WGFAVYMAVM FSGQCGSGHC NPAVTLAAAV VGKLPFRRIP FYTFFQILGA
121: FLGSLVVFAL YREKIIEYAK LNDNGALLLN TTGGIFVTNP SASHLTCFLD QVMGTALLTA
181: GAFAITDPNG WKIPDYLHPL HLAFLVYAIV GCFALNAGAA LNPARDLGPR LMIFIFGWGN
241: KAFSGANYFF WIPIVGPYIG AVIGGILYEM TIGIHLDRKS DFVVDVDYDD SHRDGKKLVA
301: YSSP