1.A.87.2.13
Transmembrane kinase receptor of 942 aas and 2 TMSs, one at the N-terminus of the protein and the second at residue 490 (Chang et al. 1992). It phosphorylates only serine and threonine residues (Schaller and Bleecker 1993) and is involved in auxin signal transduction and cell expansion as well as proliferation regulation (Dai et al. 2013). With ABP1, it is a cell surface auxin perception complex that activates ROP signaling pathways (Xu et al. 2014). It is required for auxin promotion of pavement cell interdigitation and promotes the formation of the ABP1-TMK1 protein complex (Xu et al. 2014).
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| Accession Number: | P43298 |
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| Protein Name: | Receptor protein kinase TMK1 |
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| Length: | 942 |
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| Molecular Weight: | 102388.00 |
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| Species: | Arabidopsis thaliana (Mouse-ear cress) [3702] |
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| Number of TMSs: | 3 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Single-pass type I membrane protein2 |
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| Substrate |
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1: MKKRRTFLLF SFTFLLLLSL SKADSDGDLS AMLSLKKSLN PPSSFGWSDP DPCKWTHIVC
61: TGTKRVTRIQ IGHSGLQGTL SPDLRNLSEL ERLELQWNNI SGPVPSLSGL ASLQVLMLSN
121: NNFDSIPSDV FQGLTSLQSV EIDNNPFKSW EIPESLRNAS ALQNFSANSA NVSGSLPGFL
181: GPDEFPGLSI LHLAFNNLEG ELPMSLAGSQ VQSLWLNGQK LTGDITVLQN MTGLKEVWLH
241: SNKFSGPLPD FSGLKELESL SLRDNSFTGP VPASLLSLES LKVVNLTNNH LQGPVPVFKS
301: SVSVDLDKDS NSFCLSSPGE CDPRVKSLLL IASSFDYPPR LAESWKGNDP CTNWIGIACS
361: NGNITVISLE KMELTGTISP EFGAIKSLQR IILGINNLTG MIPQELTTLP NLKTLDVSSN
421: KLFGKVPGFR SNVVVNTNGN PDIGKDKSSL SSPGSSSPSG GSGSGINGDK DRRGMKSSTF
481: IGIIVGSVLG GLLSIFLIGL LVFCWYKKRQ KRFSGSESSN AVVVHPRHSG SDNESVKITV
541: AGSSVSVGGI SDTYTLPGTS EVGDNIQMVE AGNMLISIQV LRSVTNNFSS DNILGSGGFG
601: VVYKGELHDG TKIAVKRMEN GVIAGKGFAE FKSEIAVLTK VRHRHLVTLL GYCLDGNEKL
661: LVYEYMPQGT LSRHLFEWSE EGLKPLLWKQ RLTLALDVAR GVEYLHGLAH QSFIHRDLKP
721: SNILLGDDMR AKVADFGLVR LAPEGKGSIE TRIAGTFGYL APEYAVTGRV TTKVDVYSFG
781: VILMELITGR KSLDESQPEE SIHLVSWFKR MYINKEASFK KAIDTTIDLD EETLASVHTV
841: AELAGHCCAR EPYQRPDMGH AVNILSSLVE LWKPSDQNPE DIYGIDLDMS LPQALKKWQA
901: YEGRSDLESS TSSLLPSLDN TQMSIPTRPY GFAESFTSVD GR