1.A.9.1.14
Acetylcholine receptor with two subunits, α and β, Deg-3 (564 aas)and Acr-4 (548 aas). Subunits of the non-synaptic neuronal AChR, which may play a role in chemotaxis
towards choline. After binding choline or acetylcholine, the AChR
responds by an extensive change in conformation that affects all
subunits and leads to opening of an ion-conducting channel across the
plasma membrane (Treinin et al. 1998; Yassin et al. 2001).
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| Accession Number: | P54244 |
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| Protein Name: | Acetylcholine receptor subunit alpha-type deg-3 |
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| Length: | 564 |
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| Molecular Weight: | 64927.00 |
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| Species: | Caenorhabditis elegans [6239] |
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| Number of TMSs: | 5 |
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| Location1 / Topology2 / Orientation3: |
Cell junction1 / Multi-pass membrane protein2 |
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| Substrate |
cation |
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1: MTLKIRTIII LFCVISVTTT SQSLNATLKT FDPRLLNSTA DRDIAMKNVP LVRLTRHLLS
61: PERYDVRVRP ILDHKKSLKV HISISLYQII EVDEPSQNIK LNVWMIQKWR DEYLDWNPNE
121: YGMINSTIIP FHHLWIPDTY LYNSVKMSRD ETERYMNIQA TSNYWKGEKG AELSFLYPAI
181: YTITCRLNIR FFPYDRQNCT LTISSWTNSK SALDYYADTE VSMQSFIPNE EWQVKSFKIH
241: RHEYKYACCA EPWVILQASL VIQRKPLYYL VNLIIPTSII TLVAITGFFT PASTDDDRTE
301: KINLGITTLL AMSILMLMVS DQMPTTSEFV PLIAWFYLSI IIIISIGTFL TSVVLSVQGR
361: RQYGRNPPQF IRYIFFVLLP QVLLLNVPPP LQTLWGELDD DPLNVRRRKK SHYLSRNVNN
421: GSTKMASPMS TLRVPQSAGS VSEKRQSFQM IDVTSPNSPN TARSRAPSLA PSTAKATMWE
481: GTMSALAGTN TQLRRTSNVF NKEVDEMRRK RQCSLEWEFL ATVLDRFLLI VFVGAVVIVT
541: AGLILVGRMA QYSYDHPDDR FFNV