1.A.9.1.17
Nicotinic acetylcholine receptor, Eat-2 (474 aas and 4 TMSs in a 3 + 1 arrangement)/Eat-18 in the MC
pharyngeal motor neuron involved in pharyngeal pumping. It plays a role in
the determination of life span, possibly via calorific restriction (McKay et al. 2004; Huang et al. 2004). Eat-18 may be the CRE-EAT-18 protein with TC# 8.A.47.1.3.
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| Accession Number: | Q9U298 |
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| Protein Name: | Neuronal acetylcholine receptor subunit eat-2 |
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| Length: | 474 |
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| Molecular Weight: | 55042.00 |
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| Species: | Caenorhabditis elegans [6239] |
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| Number of TMSs: | 4 |
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| Location1 / Topology2 / Orientation3: |
Cell junction1 / Multi-pass membrane protein2 |
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| Substrate |
cation |
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1: MTLKIAFFTL ILLVSIERVY SSDEEYRLLK DLREGYDPVE RPVADHRKPV NVKLRLILQQ
61: LVDVDERNQV ITLVVWNQYT WNDYKLRWSP EEYGNITTLQ IPHGTLWKPD ILLFNSANEH
121: FDASFPVHMV VSSNGDVLFA PPGIVSFSCS LSMTWFPYDQ QVCYLKFGSW TYGKKLDLQI
181: DDSDLPDGHK MDLQYYIPNG EFDLLATPAF RKSTTFLDET YVELYFHMHL KRRTMYYGLN
241: WIVPSILISL SNILGFTMPP ECGEKITLQI TNFLSVMVFL AMVSEVAPPT SESIPIIAAF
301: FSLSIVILGL SICASLIIVN IFFRHPKTHR MGDWTRYVFL EWLPWFLLMS RPEHTFCRPR
361: REEEKNDEEA GGDGTKLLEN QQHQPRPRLL VNSQLVMDST VPYLEEIIGY LKVFKAKLDD
421: DEEEEEEILN WRFMAMVIDR LSLFLFTGLI FGTTALIFAF CPNLFTDSPI VDIE