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1.A.9.4.4
Glc-4 (GluC1) glutamate receptor of 500 aas.  The x-ray structure of several states including two apo states have been solved, revealing the gating mechanism of cys-loop receptors (Althoff et al. 2014).  Ligand-induced conformational gating has been proposed (Yoluk et al. 2015).  Effects of L-glutamate, ivermectin, ethanol and anesthetics have been examined (Heusser et al. 2016).

Accession Number:Q95QT7
Protein Name:Protein GLC-4
Length:500
Molecular Weight:57905.00
Species:Caenorhabditis elegans [6239]
Number of TMSs:4
Substrate ion

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FASTA formatted sequence
1:	MKAQLYVSVL LALLVSSTAK KSKTKSCKRT AFSRHTTNYQ AWREQMTVCD LLQDYDAAVR 
61:	PSGRTPYNDT RGAVMVTTSL NIRSISAVSE KNMEFVAQFR FRQEWYDDRL RFIEHQGLLS 
121:	SDYRNFEFIH VARDQSLWIP DTFFQNEKNG WYHMLNQENR FLKIRSDGKL IYDRRLTLHL 
181:	ACSMHLSRYP MDHQNCEIAF ASYAYTTADI EYIWDVPAIQ IHEGANGALP NFEIASFKNA 
241:	SCTSKTNTGT YSCLKVEIRL NRVFSFFLLQ LYIPSSMLVG VAWVSYWIDW KSTAARVPLA 
301:	IVTLLTMITT SHAINSNLPP VSYAKSIDIW VGACVVFIFF SLIEYAVVNY VGILDEHRQM 
361:	KKAACNRSRL SNVIENDNFG ESLQSLTFSP QEKKRLIRRR PKKNMEMQEG DFEAIEMVDR 
421:	GPPRSAGLME EGWTFHDTTD LVYIGQRKRV ELVRWCSVLS SRGRAERIDI IARIIFPLAF 
481:	ILFNFAYWSI YLEEEDPDES