1.B.14.1.32
Catechol iron-siderophore uptake system, IrgA, an iron-regulated outer membrane virulence protein, of 652 aas and 1 N-terminal TMS (Wyckoff et al. 2015). It is involved in the initial step of iron uptake by
binding ferric vibriobactin, an iron chelatin siderophore that allows
V. cholerae to extract iron from the environment and takes up linear enterobactin derivatives (Wyckoff et al. 2015).
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| Accession Number: | A5F9G0 |
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| Protein Name: | Iron-regulated outer membrane virulence protein |
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| Length: | 652 |
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| Molecular Weight: | 71641.00 |
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| Species: | Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395) [345073] |
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| Location1 / Topology2 / Orientation3: |
Cell outer membrane1 |
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| Substrate |
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1: MSRFNPSPVS LSVTLGLMFS ASAFAQDATK TDETMVVTAA GYAQVIQNAP ASISVISRED
61: LESRYYRDVT DALKSVPGVT VTGGGDTTDI SIRGMGSNYT LILVDGKRQT SRQTRPNSDG
121: PGIEQGWLPP LQAIERIEVI RGPMSTLYGS DAIGGVINII TRKDQQQWSG NVQLSTVVQE
181: NRASGDEQSA NFFVTGPLSD ALSLQVYGQT TQRDEDEIEH GYGDKSLRSL TSKLNYQLNP
241: DHQLQLEAGV SAQDRENNVG KSAQSSGCRG TCSNTDNQYR RNHVAVSHQG DWQGVGQSDT
301: YLQYEENTNK SREMSIDNTV FKSTLVAPIG EHMLSFGVEG KHESLEDKTS NKISSRTHIS
361: NTQWAGFIED EWALAEQFRL TFGGRLDHDK NYGSHFSPRV YGVWNLDPLW TVKGGVSTGF
421: RAPQLREVTP DWGQVSGGGN IYGNPDLQPE TSINKELSLM YSTGSGLAAS LTAFHNDFKD
481: KITRVACPAN ICTAGPNQWG ATPTYRVNID EAETYGAEAT LSLPITESVE LSSSYTYTHS
541: EQKSGNFAGR PLLQLPKHLF NANLSWQTTD RLNSWANLNY RGKEMQPEGG ASNDDFIAPS
601: YTFIDTGVTY ALTDTATIKA AVYNLFDQEV NYAEYGYVED GRRYWLGLDI AF