1.B.14.2.14
Heme/hemoglobin receptor of 660 aas and 22 C-terminal β-strands with an N-terminal "plug" domain, ShuA. The 3-d structure is known to 2.6 Å resolution, revealing the histidyl residues in the barrel and plug that can interact with heme (Cobessi et al. 2010). The E. coli protein (OSK90542.1) is identical to this one in length and sequence.
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| Accession Number: | P72412 |
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| Protein Name: | Outer membrane heme receptor ShuA |
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| Length: | 660 |
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| Molecular Weight: | 72529.00 |
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| Species: | Shigella dysenteriae [622] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Cell outer membrane1 |
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| Substrate |
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1: MSRPQFTSLR LSLLALAVSA TLPTFAFATE TMTVTATGNA RSSFEAPMMV SVIDTSAPEN
61: QTATSATDLL RHVPGITLDG TGRTNGQDIN MRGYDHRGVL VLVDGIRQGT DTGHLNGTFL
121: DPALIKRVEI VRGPSALLYG SGALGGVISY DTVDAKDLLQ EGQSSGFRVF GTGGTGDHSL
181: GLGASAFGRT ENLDGIVAWS SRDRGDLRQS NGETAPNDES INNMLAKGTW QIDSAQSLSG
241: LVRYYNNDAR EPKNPQTVEA SESSNPMVDR STIQRDAQLS YKLAPQGNDW LNADAKIYWS
301: EVRINAQNTG SSGEYREQIT KGARLENRST LFADSFASHL LTYGGEYYRQ EQHPGGATTG
361: FPQAKIDFSS GWLQDEITLR DLPITLLGGT RYDSYRGSSD GYKDVDADKW SSRAGMTINP
421: TNWLMLFGSY AQAFRAPTMG EMYNDSKHFS IGRFYTNYWV PNPNLRPETN ETQEYGFGLR
481: FDDLMLSNDA LEFKASYFDT KAKDYISTTV DFAAATTMSY NVPNAKIWGW DVMTKYTTDL
541: FSLDVAYNRT RGKDTDTGEY ISSINPDTVT STLNIPIAHS GFSVGWVGTF ADRSTHISSS
601: YSKQPGYGVN DFYVSYQGQQ ALKGMTTTLV LGNAFDKEYW SPQGIPQDGR NGKIFVSYQW