1.B.20.1.10
Outer membrane protein component of a toxin-immunity protein module, which functions as a cellular contact-dependent growth inhibition (CDI) system. CdiB is of 584 aas and possibly two TMSs, one N-terminal, and one C-terminal. CDI modules allow bacteria to communicate with and inhibit the growth of closely related neighboring bacteria in a contact-dependent fashion. CdiB is required for secretion and assembly of the CdiA toxin protein. Expression of the cdiAIB locus in B. thailandensis confers protection against other bacteria carrying the locus; growth inhibition requires cellular contact (Nikolakakis et al. 2012). The 3-d structures of two such systems have been determined (see family description) (Guerin et al. 2020).