1.B.25.1.10
A tricarboxylate transporting porin, OdpH (Occk5) induced by and transports cis-aconitate, isocitrate and citrate; exhibits a large single channel conductance (Tamber et al., 2006; 2007). This porin exhibits a high degree of anion selectivity, and the outer core and O-antigens of LPS sterically occlude the channel entrance to decrease the diffusion constants of approaching ions (Lee et al. 2018).
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| Accession Number: | Q9I5H4 |
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| Protein Name: | OpdH |
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| Length: | 427 |
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| Molecular Weight: | 46976.00 |
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| Species: | Pseudomonas aeruginosa [287] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
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| Substrate |
citrate salt, tricarboxylic acid trianion, cis-aconitate(3-), isocitrate(3-) |
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1: MSTSLPQAAR SVRSSRSTTL TTTAVVLAGI APLGNAAGFL EDSKASLETR NFYMNRDFRD
61: GPGQSKREEW AQGFILNLQS GYTQGTVGFG LDAMGMLGVK LDSGRGRSGT GLLPKDSDGR
121: APDTYSKLGL TAKVKVSQSE LKVGTLIPKL PSVQPNNGRI FPQIFEGALL TSKEIKDLGF
181: TAGRLEKTKI RDSSDSEDLA LNDKNGRFAG VSADHFDLGG LDYKLTDQLT ASYHYSNLQD
241: VYRQHFVGLL HSWPIGPGEL TSDLRFARST DSGSAKAGGI DNKSLNGMFT YSLGNHAFGA
301: AWQRMNGDDA FPYLEGSNPY LVNFVQVNDF AGPKERSWQL RYDYDFVGLG IPGLTFMTRY
361: VKGDNVELAG QSGEGREWER NTELQYVFQS GALKNLGIRW RNATFRSNFT RDIDENRLIV
421: SYTLPIW