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1.B.3.1.3
Porin with specificity for β-glucosides, BglH of 538 aas.  High affinity binding was observed with the aromatic beta-D-glucosides arbutin and salicin as well as with gentibiose and cellobiose. Binding of maltooligosaccharides to BglH was much weaker, indicating that the binding site of BglH for carbohydrates is different from that of LamB (maltoporin) (Andersen et al. 1999).

Accession Number:P26218
Protein Name:BglH aka YieC aka B3720
Length:538
Molecular Weight:60657.00
Species:Escherichia coli [83333]
Number of TMSs:1
Location1 / Topology2 / Orientation3: Cell outer membrane1 / Multi-pass membrane protein2
Substrate salicin, hydroquinone O-beta-D-glucopyranoside, cellobiose, gentiobiose

Cross database links:

RefSeq: AP_004067.1    NP_418176.1   
Entrez Gene ID: 948228   
Pfam: PF11471    PF02264   
BioCyc: EcoCyc:EG11364-MONOMER    ECOL168927:B3720-MONOMER   
KEGG: ecj:JW3698    eco:b3720   

Gene Ontology

GO:0009279 C:cell outer membrane
GO:0005886 C:plasma membrane
GO:0046930 C:pore complex
GO:0005351 F:sugar:hydrogen symporter activity
GO:0006811 P:ion transport

References (6)

[1] “DNA sequence and analysis of 136 kilobases of the Escherichia coli genome: organizational symmetry around the origin of replication.”  Burland V.D.et.al.   7686882
[2] “The complete genome sequence of Escherichia coli K-12.”  Blattner F.R.et.al.   9278503
[3] “Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.”  Hayashi K.et.al.   16738553
[4] “Beta-glucoside (bgl) operon of Escherichia coli K-12: nucleotide sequence, genetic organization, and possible evolutionary relationship to regulatory components of two Bacillus subtilis genes.”  Schnetz K.et.al.   3034860
[5] “Identification of a cryptic porin gene in the Escherichia coli genome: expression and insertion of a monomeric form of the protein into the outer membrane.”  Wang J.et.al.   9426150
[6] “The gene bglH present in the bgl operon of Escherichia coli, responsible for uptake and fermentation of beta-glucosides encodes for a carbohydrate-specific outer membrane porin.”  Andersen C.et.al.   10027967

External Searches:

Analyze:

Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MFRRNLITSA ILLMAPLAFS AQSLAESLTV EQRLELLEKA LRETQSELKK YKDEEKKKYT 
61:	PATVNRSVST NDQGYAANPF PTSSAAKPDA VLVKNEEKNA SETGSIYSSM TLKDFSKFVK 
121:	DEIGFSYNGY YRSGWGTASH GSPKSWAIGS LGRFGNEYSG WFDLQLKQRV YNENGKRVDA 
181:	VVMMDGNVGQ QYSTGWFGDN AGGENYMQFS DMYVTTKGFL PFAPEADFWV GKHGAPKIEI 
241:	QMLDWKTQRT DAAAGVGLEN WKVGPGKIDI ALVREDVDDY DRSLQNKQQI NTNTIDLRYK 
301:	DIPLWDKATL MVSGRYVTAN ESASEKDNQD NNGYYDWKDT WMFGTSLTQK FDKGGFNEFS 
361:	FLVANNSIAS NFGRYAGASP FTTFNGRYYG DHTGGTAVRL TSQGEAYIGD HFIVANAIVY 
421:	SFGNDIYSYE TGAHSDFESI RAVVRPAYIW DQYNQTGVEL GYFTQQNKDA NSNKFNESGY 
481:	KTTLFHTFKV NTSMLTSRPE IRFYATYIKA LENELDGFTF EDNKDDQFAV GAQAEIWW