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1.B.45.1.1 Treponema porin, TP0453 of 287 aas. May be involved in ligand transport, altering membrane permeability at acidic pH (4.0 to 5.5) (Luthra et al. 2011). Incubation of the non-lipidated form with lipid vesicles increases their permeability (Hazlett et al. 2005).
Accession Number:	O67998
Protein Name:	30klp aka TP0453
Length:	287
Molecular Weight:	32000.00
Species:	Treponema pallidum [160]
Number of TMSs:	3
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	molecule

Structure:
RefSeq:	NP_218894.1
Entrez Gene ID:	2611031
BioCyc:	TPAL243276:TP_0453-MONOMER
KEGG:	tpa:TP0453
References (1) [1] “Complete genome sequence of Treponema pallidum, the syphilis spirochete.” Fraser C.M.et.al. 9665876
3K8G 3K8H 3K8I 3K8J

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MIRRRYRGCT QGAWIVSVGM LFASCTSGAW KASVDPLGVV GSGADVYLYF PVAGNENLIS 
61:	RIIENHESKA DIKKIVDRTT AVYGAFFARS KEFRLFGSGS YPYAFTNLIF SRSDGWASTK 
121:	TEHGITYYES EHTDVSIPAP HFSCVIFGSS KRERMSKMLS RLVNPDRPQL PPRFEKECTS 
181:	EGTSQTVALY IKNGGHFITK LLNFPQLNLP LGAMELYLTA RRNEYLYTLS LQLGNAKINF 
241:	PIQFLISRVL NAHIHVEGDR LIIEDGTISA ERLASVISSL YSKKGSS

1.B.45.1.1
Treponema porin, TP0453 of 287 aas. May be involved in ligand transport, altering membrane permeability at acidic pH (4.0 to 5.5) (Luthra et al. 2011). Incubation of the non-lipidated form with lipid vesicles increases their permeability (Hazlett et al. 2005).

Cross database links:

References (1)

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1.B.45.1.1Treponema porin, TP0453 of 287 aas. May be involved in ligand transport, altering membrane permeability at acidic pH (4.0 to 5.5) (Luthra et al. 2011). Incubation of the non-lipidated form with lipid vesicles increases their permeability (Hazlett et al. 2005).

Cross database links:

References (1)

External Searches:

Analyze:

1.B.45.1.1
Treponema porin, TP0453 of 287 aas. May be involved in ligand transport, altering membrane permeability at acidic pH (4.0 to 5.5) (Luthra et al. 2011). Incubation of the non-lipidated form with lipid vesicles increases their permeability (Hazlett et al. 2005).