1.B.8.1.15
VDAC1 of 276 aas, one of five isoforms.  A knock out mutation (Δvdac1) resulted in abnormal ovule formation during female gametogenesis, and both the mitochondrial transmembrane potential and ATP synthesis were reduced (Pan et al. 2014). Targeting and surface recognition of mitochondrial β-barrel proteins in yeast, humans and plants depends on the hydrophobicity of the last β-hairpin of the β-barrel, but the presence of a hydrophilic amino acid at the C-terminus of the penultimate β-strand is also required for mitochondrial targeting (Klinger et al. 2019). Kanwar et al. 2020 presented a comparative overview to provide an integrative pictureKlinger et al. 2019). Kanwar et al. 2020 presented a comparative overview to provide an integrative picture of the interactions of VDAC with different proteins in both animals and plants.