1.C.109.1.6
The 'non-conventional' hemolysin, TlyA, a pore-forming hemolysin with potent
cytotoxic activity, is of 235 aas (Javadi and Katzenmeier 2016). It causes agglutination, fusion and permeability of synthetic
liposome vesicles. Agglutination activity could also be observed
with erythrocytes before the induction of its pore-forming hemolytic
activity.
TlyA also induces disruption of liposome membranes (Lata and Chattopadhyay 2014).
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| Accession Number: | C7BYV0 |
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| Protein Name: | TlyA protein |
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| Length: | 235 |
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| Molecular Weight: | 26431.00 |
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| Species: | Helicobacter pylori (strain B38) [592205] |
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| Number of TMSs: | 1 |
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| Substrate |
molecule |
|---|
1: MRLDYALFNQ HLANSREKAK ALVLKNQVLV NKMVVSKPSF IVKEGDQIEL IAPNLLVSRA
61: GEKLGAFLEN HFIDFKEKVV LDVGASKGGF SQVALLKGAK KVLCVDVGKM QLDEGLKNDQ
121: RIECYEECDI RGFKTPEKID LVLCDVSFIS LYCILEAIVP LSGEFLALFK PQFEVGRATK
181: RNKKGVVMDK KAILNALENF KNHLKTKDFQ ILTIQESLVK GKNGNVEFFI HFKRA