1.C.111.1.14 NK cell receptor F, NKG2-F or NLRC4, of 158 aas and 1 central TMS. It may play a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells (Plougastel and Trowsdale 1997). It can associate with DAP12 (Kim et al. 2004).
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Accession Number: | O43908 |
Protein Name: | NKG2-F type II integral membrane protein |
Length: | 158 |
Molecular Weight: | 18234.00 |
Species: | Homo sapiens (Human) [9606] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Membrane1 / Single-pass type II membrane protein2 |
Substrate |
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1: MNKQRGTYSE VSLAQDPKRQ QRKLKGNKIS ISGTKQEIFQ VELNLQNASS DHQGNDKTYH
61: CKGLLPPPEK LTAEVLGIIC IVLMATVLKT IVLIPCIGVL EQNNFSLNRR MQKARHCGHC
121: PEEWITYSNS CYYIGKERRT WEERVCWPVL RRTLICFL