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1.C.123.1.4 Gasdermin C of 508 aas. The N-terminal moiety promotes pyroptosis. It may be acting by homooligomerizing within the membrane and forming pores (Ding et al. 2016). Pyroptosis and its role in central nervous system diseases have been reviewed (Hu et al. 2021).
Accession Number:	Q9BYG8
Protein Name:	Gasdermin-C
Length:	508
Molecular Weight:	57692.00
Species:	Homo sapiens (Human) [9606]
Location¹ / Topology² / Orientation³:	Cytoplasm¹
Substrate

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

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FASTA formatted sequence

1:	MPSMLERISK NLVKEIGSKD LTPVKYLLSA TKLRQFVILR KKKDSRSSFW EQSDYVPVEF 
61:	SLNDILEPSS SVLETVVTGP FHFSDIMIQK HKADMGVNVG IEVSVSGEAS VDHGCSLEFQ 
121:	IVTIPSPNLE DFQKRKLLDP EPSFLKECRR RGDNLYVVTE AVELINNTVL YDSSSVNILG 
181:	KIALWITYGK GQGQGESLRV KKKALTLQKG MVMAYKRKQL VIKEKAILIS DDDEQRTFQD 
241:	EYEISEMVGY CAARSEGLLP SFHTISPTLF NASSNDMKLK PELFLTQQFL SGHLPKYEQV 
301:	HILPVGRIEE PFWQNFKHLQ EEVFQKIKTL AQLSKDVQDV MFYSILAMLR DRGALQDLMN 
361:	MLELDSSGHL DGPGGAILKK LQQDSNHAWF NPKDPILYLL EAIMVLSDFQ HDLLACSMEK 
421:	RILLQQQELV RSILEPNFRY PWSIPFTLKP ELLAPLQSEG LAITYGLLEE CGLRMELDNP 
481:	RSTWDVEAKM PLSALYGTLS LLQQLAEA

1.C.123.1.4
Gasdermin C of 508 aas. The N-terminal moiety promotes pyroptosis. It may be acting by homooligomerizing within the membrane and forming pores (Ding et al. 2016). Pyroptosis and its role in central nervous system diseases have been reviewed (Hu et al. 2021).

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1.C.123.1.4Gasdermin C of 508 aas. The N-terminal moiety promotes pyroptosis. It may be acting by homooligomerizing within the membrane and forming pores (Ding et al. 2016). Pyroptosis and its role in central nervous system diseases have been reviewed (Hu et al. 2021).

Cross database links:

External Searches:

Analyze:

1.C.123.1.4
Gasdermin C of 508 aas. The N-terminal moiety promotes pyroptosis. It may be acting by homooligomerizing within the membrane and forming pores (Ding et al. 2016). Pyroptosis and its role in central nervous system diseases have been reviewed (Hu et al. 2021).