1.C.123.1.8
Gasdermin family protein of 252 aas and 1 or 2 central TMSs. The 3-D structure is known (7N52_A-D). Bacterial gasdermins are activated by caspase-like proteases, oligomerize into large membrane pores, and defend against pathogenic bacteriophage (Johnson et al. 2022). They mediate an ancient mechanism of prokaryotic cell death (Johnson et al. 2022).
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| Accession Number: | CHK16680 |
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| Protein Name: | CHK16680.1 Gasdermin family [Salmonella enterica subsp. enterica serovar Typhi] |
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| Length: | 253 |
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| Molecular Weight: | |
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| Species: | Salmonella enterica subsp. enterica serovar Typhi [90370] |
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| Substrate |
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1: MTFPDRPLKL YDLPVTLRYQ EEVIETGSWI DDIDPIGTIE EPANLNFMCL QHEVSEQTQL
61: LAELSKDVQE VVFSSFLHML SDRDVLYDLM KMLELNQLGH MDGPGGKILD ELRKDSSTPH
121: DVLKDLNLYL LQALLVLSDT QLCLLAQSVK MGLLPHQVEL VKSILQTNFK YSSNTPFTLQ
181: PQLLAPLQGE GLAITYELLE ECGLKMELNN PRSTWDLEAK MPLSALYGSL SFLQQLQKAN
241: SSSKPSLSPG YI