| TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
|---|---|---|---|---|
|
1.C.124.1.1 | Pandinin2 of 24 aas and 1 TMS. Forms pores and disrupts membranes of bacteria and fungi (Rodríguez et al. 2014). | Eukaryota |
Metazoa, Arthropoda | Pandinin-2 of Pandinus imperator |
|
1.C.124.1.2 | Heterin-1 of 43 aas and 1 TMS. Heterin-1 possesses potent activities against both Gram-positive and Gram-negative bacteria. Among the tested bacterial species, Heterin-1 is the most active against Bacillus megaterium and Micrococcus luteus with MICs of 4.0 μM for both (Wu et al. 2014). | Eukaryota |
Metazoa, Arthropoda | Heterin-1 of Heterometrus spinifer (Asia giant forest scorpion) (Malaysian black scorpion) |
|
1.C.124.1.3 | Venom toxin of 73 aas and 1 TMS. | Eukaryota |
Metazoa, Arthropoda | Venom toxin of Hemiscorpius lepturus (scorpion) |
|
1.C.124.1.4 | Scorpion toxin, OcyC3, of 75 aas and 1 TMS. Also called antimicrobial peptide NDBP 4.1. | Eukaryota |
Metazoa, Arthropoda | OcyC3 of Opisthacanthus cayaporum (South American scorpion) |
|
1.C.124.1.5 | Ponericin-W5 of 24 aas and 1 TMS. Has a broad spectrum of activities against both
Gram-positive and Gram-negative bacteria as well as Saccharomyces cerevisiae. It also has
insecticidal and hemolytic activities (Orivel et al. 2001). | Eukaryota |
Metazoa | Ponericin-W5 of Pachycondyla goeldii (Ponerine ant) |
|
1.C.124.1.6 | Antimicrobial peptide, AMP, of 76 aas and 1 N-terminal TMS. It is similar to a characterized AMP that forms toroidal pores, reported by Bertelsen et al. 2023. | Eukaryota |
Metazoa, Arthropoda | AMP of Pandinus cavimanus (Tanzanian red clawed scorpion) |
|
1.C.124.2.1 | Pandinin 1, Pin1, of 44 aas and 0 TMSs. Pin1 is located at the membrane-water interface, approximately parallel to the bilayer surface. Solid-state NMR results correlated well with the observed biological activity of pin1 in red blood cells and bacteria (Nomura et al. 2005). Pin-1 and Pin-2 are not demonstrably homologous. However, Pin1 shows 30% identity with a central part of 1.C.17.2.2. | Eukaryota |
Metazoa, Arthropoda | Pin-1 of Pandinus imperator |