1.C.139.1.1
The Candida albicans virulence factor, candidalysin (CA) of 271 aas with 1 N-terminal TMS followed by 4 putative equidistant TMSs. It polymerizes in solution to form membrane pores and damage epithelial cells (Russell et al. 2022) (see famiy description for details).
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| Accession Number: | Q07730 |
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| Protein Name: | Extent of cell elongation protein 1 |
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| Length: | 271 |
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| Molecular Weight: | 28878.00 |
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| Species: | Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) [237561] |
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| Number of TMSs: | 1 |
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| Location1 / Topology2 / Orientation3: |
Host cell membrane1 / Single-pass membrane protein2 |
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| Substrate |
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1: MKFSKIACAT VFALSSQAAI IHHAPEFNMK RDVAPAAPAA PADQAPTVPA PQEFNTAITK
61: RSIIGIIMGI LGNIPQVIQI IMSIVKAFKG NKREDIDSVV AGIIADMPFV VRAVDTAMTS
121: VASTKRDGAN DDVANAVVRL PEIVARVATG VQQSIENAKR DGVPDVGLNL VANAPRLISN
181: VFDGVSETVQ QAKRDGLEDF LDELLQRLPQ LITRSAESAL KDSQPVKRDA GSVALSNLIK
241: KSIETVGIEN AAQIVSERDI SSLIEEYFGK A