1.C.2.2.3
Bacillus thuringiensis subsp. medellin produces the Cry11Bb protein of 94 kDa (750 aas), which is toxic for mosquito larvae due to permeabilization of the plasma membrane of midgut epithelial cells (Lemeshko et al. 2005). A membrane channel-forming peptide, BTM-P1, has been derived from this protein (Lemeshko et al. 2005).
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| Accession Number: | Q9ZIU5 |
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| Protein Name: | Pesticidal crystal protein Cry11Bb |
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| Length: | 750 |
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| Molecular Weight: | 84408.00 |
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| Species: | Bacillus thuringiensis subsp. medellin [79672] |
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| Substrate |
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1: MENNSFNVLA NNNMSSFPLF NSKIEPSIAP ALIAVAPIAK YLATALAKWA LKQGFAKLKS
61: EIFPGNETAT MEKVRLEVQT ILNQTLQTDR VATLKAEYEG FIHLGKVFTD YVSQSTFTPA
121: TAKTHFLNMS NLLIQRLPQF EIAGYEGVSI SLFTQMCTLH LGLLKDGILA GSDWGFTPED
181: KDSLICQFNR YVNEYNTRMM GLYSIEFGRL LAKNLNEALN FRNMCSLYVF PFSEAWYLLR
241: YEGTKLENTL SLWNFVGEDI GGILHNDWKG ALYKLLMGAT NQRLANVRFN YSYFSDTQGT
301: IHRENILGAH PTYNGEQTPT GWIGNGRLGR FSAPYSNELE ITKVEQEITY NNKGDHSNSI
361: VPANTRNEIL TATVPITADP FFKTADINWR YFSQGLYYGW NIKFDDRVIL NSRVPGGIPS
421: NRLEYDGYYI RAVSACPRNV PLSYNHNYLT LTYNRLEYDA PTTQNIIVGF SPNNTKSFYA
481: RNSHYLSATN DAYVIPALQF ATVSDRSFLE DTPDQATDGS IKFTETVLGN EAKYSIRLNT
541: GFNTATRYRL VIRFKATARL AAGIRVRSQN SGNNRLLGGI PVEGNSGWVD YITDSFTFND
601: LGITTASTNA FFSIDSDGVN ASQQWYLSKL ILVKDFVNNS GFRNQVPLAP YVIARCPNTF
661: FVSNNTSSGY EQGYNDNYNQ NTSSGYEQGY NDNYNQNTSS GYEQGYNDNY NQNTSSGYEQ
721: GYNDNYNQNT SSGYEQGYND NYNQNTSSGV