Membrane protein, Rv1234, of 175 aas and 2 TMSs. It is a non-essential protein that is induced during dormancy. A homologue in Micrococcus luteus, called Hyp730 (TC# 1.C.53.2.11), has been studied. Structural homology comparisons showed that Hyp730 is highly conserved and non-redundant in G+C rich Actinobacteria and other bacteria, and might be involved, under stress conditions, in an energy-saving process involving respiration during dormancy (Fannin et al. 2021).
|Protein Name:||Probable transmembrane protein|
|Species:||Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)  |
|Number of TMSs:||2|
1: MTSPFQPRQV PGSTPAAAGA GRRGVPALPT PPKGWPVGSY PTYAEAQRAV DYLSEQQFPV
61: QQVTIVGVDL MQVERVTGRL TWPKVLGGGV LSGAWLGLFI GLVLGFFSPN PWSALVTGLV
121: AGVFFGLITS AVPYAMARGT RDFSSTMQLV AGRYDVLCDP QNAEKARDLL ARLAI