TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
---|---|---|---|---|
1.C.76.1.1 | Maculatin 1.1 (21 aas); similar to caerin (1.C.52.1.9) (Fernandez et al., 2008; Mechler et al., 2007). Maculatins self assemble in parallel to form pores in phospholipid bilayers (Sani et al. 2020). | Eukaryota |
Metazoa, Chordata | Maculatin 1.1 of Litoria genimaculata (P82066) |
1.C.76.1.2 | Maculatin-2.1 of 18 aas and 1 TMS. Maculatins self assemble in parallel to form pores in phospholipid bilayers (Sani et al. 2020). | Eukaryota |
Metazoa, Chordata | Maculatin-2.1 of Litoria genimaculata (Green-eyed tree frog) |
1.C.76.1.3 | Aurein-1.2 of 13 aas and 1 TMS. It shows antimicrobial activity against B. cereus, L. lactis, L. innocua, M. luteus, P. multocida, S. aureus, S. epidermidis and S. uberis, and it has anticancer activity (Rozek et al. 2000). It probably acts by disturbing membrane functions with its amphipathic structure. The 3d structure in a micelle is known (Wang et al. 2005). Flower-like nanomicelles have been used for the oral delivery of several antitumor drugs (Hu et al. 2023). | Eukaryota |
Metazoa, Chordata | Aurein-1.2 of Litoria aurea (bell frog) |
1.C.76.1.4 | Citropin-1.2 of 16 aas and 1 TMS. | Eukaryota |
Metazoa, Chordata | Citropin-1.2 of Litoria citropa (Australian blue mountains tree frog) |
1.C.76.1.5 | Uperin-2.3 of 19 aas and 1 TMS. It shows medium antibacterial activities against B. cereus, L. mesenteriodes and S. uberis. | Eukaryota |
Metazoa, Chordata | Uperin-2.3 of Uperoleia inundata (Floodplain toadlet) |