TCDB is operated by the Saier Lab Bioinformatics Group
TCIDNameDomainKingdom/PhylumProtein(s)
1.C.76.1.1









Maculatin 1.1 (21 aas); similar to caerin (1.C.52.1.9) (Fernandez et al., 2008; Mechler et al., 2007). Maculatins self assemble in parallel to form pores in phospholipid bilayers (Sani et al. 2020).

Eukaryota
Metazoa, Chordata
Maculatin 1.1 of Litoria genimaculata (P82066)
1.C.76.1.2









Maculatin-2.1 of 18 aas and 1 TMS. Maculatins self assemble in parallel to form pores in phospholipid bilayers (Sani et al. 2020).

Eukaryota
Metazoa, Chordata
Maculatin-2.1 of Litoria genimaculata (Green-eyed tree frog)
1.C.76.1.3









Aurein-1.2 of 13 aas and 1 TMS. It shows antimicrobial activity against B. cereus, L. lactis, L. innocua, M. luteus, P. multocida, S. aureus, S. epidermidis and S. uberis, and it has anticancer activity (Rozek et al. 2000). It probably acts by disturbing membrane functions with its amphipathic structure.  The 3d structure in a micelle is known (Wang et al. 2005). Flower-like nanomicelles have been used for the oral delivery of several antitumor drugs (Hu et al. 2023).

Eukaryota
Metazoa, Chordata
Aurein-1.2 of Litoria aurea (bell frog)
1.C.76.1.4









Citropin-1.2 of 16 aas and 1 TMS.

Eukaryota
Metazoa, Chordata
Citropin-1.2 of Litoria citropa (Australian blue mountains tree frog)
1.C.76.1.5









Uperin-2.3 of 19 aas and 1 TMS.  It shows medium antibacterial activities against B. cereus, L. mesenteriodes and S. uberis.

Eukaryota
Metazoa, Chordata
Uperin-2.3 of Uperoleia inundata (Floodplain toadlet)