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|---|---|
| Accession Number: | P02808 |
| Protein Name: | Statherin aka STATH |
| Length: | 62 |
| Molecular Weight: | 7304.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 1 |
| Location1 / Topology2 / Orientation3: | Secreted1 |
| Substrate | ATP |
Cross database links:
| RefSeq: | NP_001009181.1 NP_003145.1 |
|---|---|
| Entrez Gene ID: | 6779 |
| Pfam: | PF03875 |
| OMIM: |
184470 gene |
| KEGG: | hsa:6779 |
Gene Ontology
GO:0005576
C:extracellular region
GO:0030197
F:extracellular matrix constituent, lubricant...
GO:0046848
F:hydroxyapatite binding
GO:0005515
F:protein binding
GO:0030345
F:structural constituent of tooth enamel
GO:0031214
P:biomineral formation
GO:0030502
P:negative regulation of bone mineralization
GO:0001503
P:ossification
GO:0046541
P:saliva secretion
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References (8)[1] “cDNA cloning and chromosomal localization (4q11-13) of a gene for statherin, a regulator of calcium in saliva.” Sabatinai L.et.al. 3502720 [2] “Human submandibular gland statherin and basic histidine-rich peptide are encoded by highly abundant mRNA's derived from a common ancestral sequence.” Dickinson D.P.et.al. 3426601 [3] “Structure and sequence determination of the gene encoding human salivary statherin.” Sabatini L.M.et.al. 2373369 [4] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [6] “Complete covalent structure of statherin, a tyrosine-rich acidic peptide which inhibits calcium phosphate precipitation from human parotid saliva.” Schlesinger D.H.et.al. 838735 [7] “Molecular basis of salivary proline-rich protein and peptide synthesis: cell-free translations and processing of human and macaque statherin mRNAs and partial amino acid sequence of their signal peptides.” Oppenheim F.G.et.al. 3476566 [8] “HPLC-MS characterization of cyclo-statherin Q-37, a specific cyclization product of human salivary statherin generated by transglutaminase 2.” Cabras T.et.al. 17313100
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MKFLVFAFIL ALMVSMIGAD SSEEKFLRRI GRFGYGYGPY QPVPEQPLYP QPYQPQYQQY 61: TF