1.C.85.1.8 β-Defensin 3 (BD3) of 63 aas and 1 TMS (Colavita et al. 2015). Sass et al. 2008 have proposed that interference with the organisation of membrane-bound multienzyme complexes such as the electron transport chain and the cell wall biosynthetic complex rather than on formation of defined transmembrane
pores is responsible for death of Staphylococcus aureus (Sass et al. 2008). However, BD3 selectively inhibits mouse Kv1.6 and human KCNQ1/KCNE1 channels with IC50 values of 0.6 μM and 1.2 μM, respectively (Zhang et al. 2018).
|
Accession Number: | Q9WTL0 |
Protein Name: | Beta-defensin 3 |
Length: | 63 |
Molecular Weight: | 7126.00 |
Species: | Mus musculus (Mouse) [10090] |
Number of TMSs: | 1 |
Location1 / Topology2 / Orientation3: |
Secreted1 |
Substrate |
molecule |
---|
1: MRIHYLLFAF LLVLLSPPAA FSKKINNPVS CLRKGGRCWN RCIGNTRQIG SCGVPFLKCC
61: KRK