1.C.85.1.9
Canine β-defensin-1, cBD1, of 41 aas and 1 N-terminal TMS.  Production of beta-defensins constitutes an important role in skin defense, and variable expression of three cBDs in different organ systems of the dog has been observed. In skin, three beta-defensins, cBD1, cBD103 and cBD107, were extensively expressed (van Damme et al. 2009). There is a possible defect in the innate immune response of dogs with atopic dermatitis.  cDB1 may be a marker for Leishmania infantum infection in dogs (da Silva et al. 2017).