TCDB » SEARCH

« See all members of the family

1.C.96.1.1 The haemolytic lectin, CEL-III (Uchida et al. 2004). CEL-III heptamerizes via a large structural transition from alpha-helices to a beta-barrel during the transmembrane pore-formation process (Unno et al. 2014).
Accession Number:	Q868M7
Protein Name:	Hemolytic lectin CEL-III
Length:	442
Molecular Weight:	48456.00
Species:	Cucumaria echinata (Sea cucumber) [40245]
Location¹ / Topology² / Orientation³:	Cytoplasmic vesicle¹ / Multi-pass membrane protein²
Substrate	molecule

Structure:
Pfam:	PF00652
Gene Ontology GO:0005529 F:sugar binding
References (2) [1] “Primary structure of hemolytic lectin CEL-III from marine invertebrate Cucumaria echinata and its cDNA: structural similarity to the B-chain from plant lectin, ricin.” Nakano M.et.al. 10561549 [2] “Crystal structure of the hemolytic lectin CEL-III isolated from the marine invertebrate Cucumaria echinata: implications of domain structure for its membrane pore-formation mechanism.” Uchida T.et.al. 15194688
1VCL 2Z48 2Z49 3W9T

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MVSLVPCGFA QVLCTNPLDI GELRNYKSKQ CVDIVGNQGS GNIATHDCDG LSDQQIIMCG 
61:	DGTIRNEARN YCFTPDGSGN ANVMSSPCTL YPEIPSSQRW RLGRKKAFTD NGGIEQVATE 
121:	IINLASGKCL DVEGSDGTGD IGVYDCQNLD DQYFYIRSRG PELFYGRLRN EKSDLCLDVE 
181:	GSEGKGNVLM YSCEDNLDQW FRYYENGEIV NAKQGMCLDV EGSDGSGNVG IYRCDDLRDQ 
241:	MWSRPNAYCN GDYCSFLNKE SNKCLDVSGD QGTGDVGTWQ CDGLPDQRFK WVFDDWEVPT 
301:	ATWNMVGCDQ NGKVSQQISN TISFSSTVTA GVAVEVSSTI EKGVIFAKAS VSVKVTASLS 
361:	KAWTNSQSGT TAITYTCDNY DSDEEFTRGC MWQLAIETTE VKSGDLLVWN PQIIKCTRSN 
421:	TAPGCAPFTK CANEDCTFCT DI

1.C.96.1.1
The haemolytic lectin, CEL-III (Uchida et al. 2004). CEL-III heptamerizes via a large structural transition from alpha-helices to a beta-barrel during the transmembrane pore-formation process (Unno et al. 2014).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

1.C.96.1.1The haemolytic lectin, CEL-III (Uchida et al. 2004). CEL-III heptamerizes via a large structural transition from alpha-helices to a beta-barrel during the transmembrane pore-formation process (Unno et al. 2014).

Cross database links:

Gene Ontology

References (2)

External Searches:

Analyze:

1.C.96.1.1
The haemolytic lectin, CEL-III (Uchida et al. 2004). CEL-III heptamerizes via a large structural transition from alpha-helices to a beta-barrel during the transmembrane pore-formation process (Unno et al. 2014).