1.E.14.1.17 Putative holin (or anti-holin) of 146 aas and 4 TMSs, YsbA or LrgA. YsbA is important for acetic acid induced biofilm formation (Chen et al. 2015) and for pyruvate utilization (van den Esker et al. 2016). van den Esker et al. 2016 proposed that YsbA is a pyruvate transporter. Thus, there is some question about the function of this protein and other members of this family.
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Accession Number: | P94515 |
Protein Name: | Antiholin-like protein LrgA |
Length: | 146 |
Molecular Weight: | 15711.00 |
Species: | Bacillus subtilis (strain 168) [224308] |
Number of TMSs: | 4 |
Location1 / Topology2 / Orientation3: |
Cell membrane1 / Multi-pass membrane protein2 |
Substrate |
acetic acid |
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1: MSAKKVYGFL TQAFIFAVIM LVSNMIAAIV PIPIPASVVG LVLLFLLLCL KVIKLEQVET
61: LGTSLTSLIG FLFVPSGISV MNSLGVMQQY GLQIVLVILL ATIILLGATG LFSQLILSLS
121: GKRKTEADMK TKTVQSPQNN NELVHH