1.F.1.3.1
Synaptobrevin homolog YKT6 of 198 aas and possibly one N-terminal TMS. It is a vesicular soluble NSF attachment protein receptor (v-SNARE) mediating vesicle docking and fusion to a specific acceptor cellular compartment. It functions in endoplasmic reticulum to Golgi transport, and is part of a SNARE complex composed of GOSR1, GOSR2 and STX5. It functions in early/recycling endosome to TGN transport as part of a SNARE complex composed of BET1L, GOSR1 and STX5 (Tai et al. 2004). It has S-palmitoyl transferase activity and is prenylated (McNew et al. 1997). Double prenylation of Ykt6 is required for lysosomal hydrolase trafficking (Sakata et al. 2021).