TCID | Name | Domain | Kingdom/Phylum | Protein(s) |
---|---|---|---|---|
1.G.19.1.1 | The rotavirus A membrane fusion protein complex including VP5 and 8, derived by proteolysis of VP4, as well as VP7, VP6 and VP2. VP5, 8 and 7 may play primary roles while VP6 and 2 play secondary roles (Gilbert and Greenberg 1998; Golantsova et al. 2004; Settembre et al. 2011; Elaid et al. 2014). These proteins from different viral strains may be very divergent in sequence. | Viruses |
Orthornavirae, Duplornaviricota | Fusion complex of rotavirus A VP4 (776 aas; P12473) cleaved to VP5 (486 aas; Q88301) and VP8 (247 aas; Q86512) VP7 (326 aas; 2 N-terminal TMSs; Q8AZ15) VP6 (397 aas; M1KB04) VP2 (894 aas; M1KTL8) |
1.G.19.1.2 | Major outer capsid protein VP4, partial, of 696 aas and 0 - 2 TMSs. The GCRV-II virus major outer capsid protein VP4 promotes cell apoptosis by VDAC2-mediated calcium pathway facilitation (Zhao et al. 2025). | Viruses |
Orthornavirae, Duplornaviricota | VP4 of human rotavirus A |