1.S.10.1.1 Nanocompartment encapsulin of 262 aas and 2 quite hydrophobic peaks at residues 40 and 155. The nanocompartment contains the dye-decolorizing peroxidase DyP. This nanocompartment is important for the ability of Mtb to
resist oxidative stress in low pH environments, including during
infection of host cells and upon treatment with a clinically relevant
antibiotic (Lien et al. 2021). Shell component of a type 2A encapsulin nanocompartment. It forms
nanocompartments about 24 nm in diameter from 60 monomers, and probably encapsulates at least cysteine desulfurase (CyD, Acc # O32975) and allows passage of cysteine into its interior, probably involved in sulfur metabolism.
|
Accession Number: | O06797 |
Protein Name: | Encapsulin nanocompartment protein Rv1762c |
Length: | 262 |
Molecular Weight: | 28755.00 |
Species: | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) [83332] |
Location1 / Topology2 / Orientation3: |
Encapsulin nanocompartment1 |
Substrate |
cysteine |
---|
1: MQSSSLDPVA SERLSHAEKS FTSDLSINEF ALLHGAGFEP IELVMGVSVY HVGFQFSGMR
61: QQQELGVLTE ATYRARWNAM ARMQAEADAL KADGIVGVRL NWRHHGEGGE HLEFMAVGTA
121: VRYTAKPGAF RRPNGQAFSS HLSGQDMVTL LRSGFAPVAF VMGNCVFHIA VQGFMQTLRQ
181: IGRNMEMPQW TQGNYQAREL AMSRMQSEAE RDGATGVVGV HFAISNYAWG VHTVEFYTAG
241: TAVRRTGSGE TITPSFVLPM DS