2.A.1.1.137
Glycerol:H+ symporter,WaStl1, of 561 aas and 12 TMSs. WaStl1 is a concentrative glycerol-H+ symporter with twice the
affinity of S. cerevisiae. It is
repressed by glucose and derepressed/induced by glycerol. This yeast, aerobically growing on glycerol, was
found to produce ethanol, providing a redox escape to compensate the redox imbalance at the level of cyanide-resistant respiration (CRR) and glycerol 3P shuttle (da Cunha et al. 2019).
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| Accession Number: | AKU75155.2 |
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| Protein Name: | AKU75155.2 glycerol symporter [Wickerhamomyces anomalus] |
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| Length: | 562 |
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| Molecular Weight: | |
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| Species: | Wickerhamomyces anomalus [4927] |
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| Number of TMSs: | 12 |
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| Substrate |
glycerol |
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1: MGFDWKSRTN TSGLSGRALR VSVTLTATLG FSLFGYDQGL MSGLITGHEF NYEFPATKGN
61: SVNQGAVTAC YEIGCFFGAL FAMFRGERIG RRPLIILGAF IIIIGTLISV TAYRDDWGTG
121: QFVVGRVITG IGNGMNTATI PVWQSEMSKP EKRGMLVNLE GSVVAIGTFV AYWVDFGMSY
181: VNNSSQWRFP VAFQIFFAFF VMIGALQLPE SPRWLLSKGR REEAVFVLAA LNDVPIDDEG
241: VDEEATAIQD AVEKVSKKQI SIKEVFTGGK TQHFRRMLIG SSTQFFQQFT GCNAAIYYST
301: VLFEQTIGLT GKLPLILGGV FATIYALSTI PSFFLIEKLG RRNLFLIGAT GQGCSFIITF
361: GCLVKDTTQN AKGAAVGLFL FIVFFAFTIL PLPWVYPPEI NPLRTRTVAS AISTCTNWLT
421: NFAVVMFTPV FIANARWGCY LFFAVMNFIF VPIIFFFYPE TAGRSLEEMD IMFAKAHVEK
481: KPVWRVAQTM PKMNHREVER AAVELGLFDE IEFQNDGFDD KASASIPDAE KEGTSGTDTP
541: DSQENNNNHS GLFVKKGDDN V