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2.A.1.1.24 Hexose (Glucose and Fructose) transporter, PfHT1 of 504 aas and 12 TMSs. This is the only hexose transporter, and it is found in the plasma membrane. It is an antimalarial drug target (Meier et al. 2018; Wunderlich 2022).
Accession Number:	O97467
Protein Name:	PfHT1 aka HT1 aka PFB0210C
Length:	504
Molecular Weight:	56417.00
Species:	Plasmodium falciparum [5833]
Number of TMSs:	12
Location¹ / Topology² / Orientation³:	Membrane¹ / Multi-pass membrane protein²
Substrate	hexose

Structure:
Pfam:	PF00083
Gene Ontology GO:0016021 C:integral to membrane GO:0022891 F:substrate-specific transmembrane transporte... GO:0008643 P:carbohydrate transport GO:0055085 P:transmembrane transport
References (1) [1] “Intraerythrocytic Plasmodium falciparum expresses a high affinity facilitative hexose transporter.” Woodrow C.J.et.al. 10066789
6M20 6M2L 6RW3

UniProt (Universal Protein Resource)
CDD Search (Conserved Domain Database)

Predict TMSs (Predict number of transmembrane segments)

FASTA formatted sequence

1:	MTKSSKDICS ENEGKKNGKS GFFSTSFKYV LSACIASFIF GYQVSVLNTI KNFIVVEFEW 
61:	CKGEKDRLNC SNNTIQSSFL LASVFIGAVL GCGFSGYLVQ FGRRLSLLII YNFFFLVSIL 
121:	TSITHHFHTI LFARLLSGFG IGLVTVSVPM YISEMTHKDK KGAYGVMHQL FITFGIFVAV 
181:	MLGLAMGEGP KADSTEPLTS FAKLWWRLMF LFPSVISLIG ILALVVFFKE ETPYFLFEKG 
241:	RIEESKNILK KIYETDNVDE PLNAIKEAVE QNESAKKNSL SLLSALKIPS YRYVIILGCL 
301:	LSGLQQFTGI NVLVSNSNEL YKEFLDSHLI TILSVVMTAV NFLMTFPAIY IVEKLGRKTL 
361:	LLWGCVGVLV AYLPTAIANE INRNSNFVKI LSIVATFVMI ISFAVSYGPV LWIYLHEMFP 
421:	SEIKDSAASL ASLVNWVCAI IVVFPSDIII KKSPSILFIV FSVMSILTFF FIFFFIKETK 
481:	GGEIGTSPYI TMEERQKHMT KSVV

2.A.1.1.24
Hexose (Glucose and Fructose) transporter, PfHT1 of 504 aas and 12 TMSs. This is the only hexose transporter, and it is found in the plasma membrane. It is an antimalarial drug target (Meier et al. 2018; Wunderlich 2022).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.1.1.24Hexose (Glucose and Fructose) transporter, PfHT1 of 504 aas and 12 TMSs. This is the only hexose transporter, and it is found in the plasma membrane. It is an antimalarial drug target (Meier et al. 2018; Wunderlich 2022).

Cross database links:

Gene Ontology

References (1)

External Searches:

Analyze:

2.A.1.1.24
Hexose (Glucose and Fructose) transporter, PfHT1 of 504 aas and 12 TMSs. This is the only hexose transporter, and it is found in the plasma membrane. It is an antimalarial drug target (Meier et al. 2018; Wunderlich 2022).