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|---|---|
| Accession Number: | O95528 |
| Protein Name: | Glucose transporter type 10 aka GLUT10 |
| Length: | 541 |
| Molecular Weight: | 56911.00 |
| Species: | Homo sapiens (Human) [9606] |
| Number of TMSs: | 10 |
| Location1 / Topology2 / Orientation3: | Endomembrane system1 / Multi-pass membrane protein2 |
| Substrate | UDP-2-deoxyglucose, glucose |
Cross database links:
| RefSeq: | NP_110404.1 |
|---|---|
| Entrez Gene ID: | 81031 |
| Pfam: | PF00083 |
| OMIM: |
208050 phenotype 606145 gene |
| KEGG: | hsa:81031 hsa:81031 |
Gene Ontology
GO:0012505
C:endomembrane system
GO:0016021
C:integral to membrane
GO:0048471
C:perinuclear region of cytoplasm
GO:0005351
F:sugar:hydrogen symporter activity
GO:0015758
P:glucose transport
GO:0055085
P:transmembrane transport
GO:0005886
C:plasma membrane
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References (16)[1] “Molecular cloning of a novel member of the GLUT family of transporters, SLC2A10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility.” McVie-Wylie A.J.et.al. 11247674 [2] “Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1.” Dawson P.A.et.al. 11592815 [3] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [4] “The DNA sequence and comparative analysis of human chromosome 20.” Deloukas P.et.al. 11780052 [5] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [6] “Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary traits.” Andersen G.et.al. 12941788 [7] “Mutations in the facilitative glucose transporter GLUT10 alter angiogenesis and cause arterial tortuosity syndrome.” Coucke P.J.et.al. 16550171 [8] “Arterial tortuosity syndrome: clinical and molecular findings in 12 newly identified families.” Callewaert B.L.et.al. 17935213 [9] “Molecular cloning of a novel member of the GLUT family of transporters, SLC2A10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility.” McVie-Wylie A.J.et.al. 11247674 [10] “Sequence and functional analysis of GLUT10: a glucose transporter in the Type 2 diabetes-linked region of chromosome 20q12-13.1.” Dawson P.A.et.al. 11592815 [11] “Complete sequencing and characterization of 21,243 full-length human cDNAs.” Ota T.et.al. 14702039 [12] “The DNA sequence and comparative analysis of human chromosome 20.” Deloukas P.et.al. 11780052 [13] “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).” The MGC Project Teamet.al. 15489334 [14] “Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary traits.” Andersen G.et.al. 12941788 | |
External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MGHSPPVLPL CASVSLLGGL TFGYELAVIS GALLPLQLDF GLSCLEQEFL VGSLLLGALL 61: ASLVGGFLID CYGRKQAILG SNLVLLAGSL TLGLAGSLAW LVLGRAVVGF AISLSSMACC 121: IYVSELVGPR QRGVLVSLYE AGITVGILLS YALNYALAGT PWGWRHMFGW ATAPAVLQSL 181: SLLFLPAGTD ETATHKDLIP LQGGEAPKLG PGRPRYSFLD LFRARDNMRG RTTVGLGLVL 241: FQQLTGQPNV LCYASTIFSS VGFHGGSSAV LASVGLGAVK VAATLTAMGL VDRAGRRALL 301: LAGCALMALS VSGIGLVSFA VPMDSGPSCL AVPNATGQTG LPGDSGLLQD SSLPPIPRTN 361: EDQREPILST AKKTKPHPRS GDPSAPPRLA LSSALPGPPL PARGHALLRW TALLCLMVFV 421: SAFSFGFGPV TWLVLSEIYP VEIRGRAFAF CNSFNWAANL FISLSFLDLI GTIGLSWTFL 481: LYGLTAVLGL GFIYLFVPET KGQSLAEIDQ QFQKRRFTLS FGHRQNSTGI PYSRIEISAA 541: S