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2.A.1.1.83
The cellobiose/cellotriose/cellodextrin/lactose transporter, Cdt-2, of 525 aas and 12 TMSs. It functions by facilitated diffusion but with low efficiency and high affinity (Km = 3 μM). Mutations can increase its activity substantially (Lian et al. 2014). It appears to be capable of catalyzing efflux of 2'-fucosyllactose (2'FL), the most abundant oligosaccharide in human breast milk, following genetic engineering (Hollands et al. 2019).

Accession Number:Q7SD12
Protein Name:Putative uncharacterized protein
Length:525
Molecular Weight:58776.00
Species:Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) [367110]
Number of TMSs:12
Substrate Cellobiose, Cellodextrin

Cross database links:

Entrez Gene ID: 3880022   
Pfam: PF00083   
KEGG: ncr:NCU08114   

Gene Ontology

GO:0016021 C:integral to membrane
GO:0022891 F:substrate-specific transmembrane transporter activity

References (1)

[1] “The genome sequence of the filamentous fungus Neurospora crassa.”  Galagan J.E.et.al.   12712197

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Predict TMSs (Predict number of transmembrane segments)
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FASTA formatted sequence
1:	MGIFNKKPVA QAVDLNQIQE EAPQFERVDW KKDPGLRKLY FYAFILCIAS ATTGYDGMFF 
61:	NSVQNFETWI KYFGDPRGSE LGLLGALYQI GSIGSIPFVP LLTDNFGRKT PIIIGCVIMI 
121:	VGAVLQATAK NLDTFMGGRT MLGFGNSLAQ IASPMLLTEL AHPQHRARLT TIYNCLWNVG 
181:	ALVVSWLAFG TNYINNDWSW RIPALLQAFP SIIQLLGIWW VPESPRFLIA KDKHDEALHI 
241:	LAKYHANGDP NHPTVQFEFR EIKETIRLEM ESTKNSSYLD FFKSRGNRYR LAILLSLGFF 
301:	SQWSGNAIIS NYSSKLYETA GVTDSTAKLG LSAGQTGLAL IVSVTMALLV DKLGRRLAFL 
361:	ASTGGMCGTF VIWTLTAGLY GEHRLKGADK AMIFFIWVFG IFYSLAWSGL LVGYAIEILP 
421:	YRLRGKGLMV MNMSVQCALT LNTYANPVAF DYFGPDHSWK LYLIYTCWIA AEFVFVFFMY 
481:	VETKGPTLEE LAKVIDGDEA DVAHIDIHQV EKEVEIHEHE GKSVA