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2.A.1.1.98
Sugar transporter ERD6-like 6, ERD6L6, of 487 aas and 12 TMSs.  It is 92% identical to ERD6L4 (488 aas and 12 TMSs) of A. thaliana, and ERD6-like 4 is candidate gene for foliar water-soluble carbohydrate accumulation in Trifolium repens (Pearson et al. 2022). Vacuolar sugar transporter EARLY RESPONSE TO DEHYDRATION 6-LIKE4 affects fructose signaling and plant growth (Khan et al. 2023). Regulation of intracellular sugar homeostasis is maintained by regulation of activities of sugar import and export proteins residing at the tonoplast. ERDL4 protein resides in the vacuolar membrane in Arabidopsis thaliana. Gene expression and subcellular fractionation studies indicated that ERDL4 participates in fructose allocation across the tonoplast, and modification of cytosolic fructose levels influences plant organ development and stress tolerance (Khan et al. 2023). .

Accession Number:Q9FRL3
Protein Name:Sugar transporter ERD6-like 6
Length:487
Molecular Weight:52901.00
Species:Arabidopsis thaliana (Mouse-ear cress) [3702]
Number of TMSs:12
Location1 / Topology2 / Orientation3: Membrane1 / Multi-pass membrane protein2
Substrate UDP-sugar, fructose

Cross database links:

Entrez Gene ID: 843859   
Pfam: PF00083   
KEGG: ath:AT1G75220   

Gene Ontology

GO:0005794 C:Golgi apparatus
GO:0016021 C:integral to membrane
GO:0005774 C:vacuolar membrane
GO:0022891 F:substrate-specific transmembrane transporter activity
GO:0008643 P:carbohydrate transport

References (3)

[1] “Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.”  Theologis A.et.al.   11130712
[2] “Empirical analysis of transcriptional activity in the Arabidopsis genome.”  Yamada K.et.al.   14593172
[3] “The monosaccharide transporter gene family in land plants is ancient and shows differential subfamily expression and expansion across lineages.”  Johnson D.A.et.al.   16923188

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FASTA formatted sequence
1:	MSFRDDNEEA RNDLRRPFIH TGSWYRMGSR QSSMMGSSQV IRDSSISVLA CVLIVALGPI 
61:	QFGFTCGYSS PTQAAITKDL GLTVSEYSVF GSLSNVGAMV GAIASGQIAE YIGRKGSLMI 
121:	AAIPNIIGWL CISFAKDTSF LYMGRLLEGF GVGIISYTVP VYIAEIAPQN MRGGLGSVNQ 
181:	LSVTIGIMLA YLLGLFVPWR ILAVLGILPC TLLIPGLFFI PESPRWLAKM GMTDEFETSL 
241:	QVLRGFETDI TVEVNEIKRS VASSTKRNTV RFVDLKRRRY YFPLMVGIGL LVLQQLGGIN 
301:	GVLFYSSTIF ESAGVTSSNA ATFGVGAIQV VATAISTWLV DKAGRRLLLT ISSVGMTISL 
361:	VIVAAAFYLK EFVSPDSDMY SWLSILSVVG VVAMVVFFSL GMGPIPWLIM SEILPVNIKG 
421:	LAGSIATLAN WFFSWLITMT ANLLLAWSSG GTFTLYGLVC AFTVVFVTLW VPETKGKTLE 
481:	ELQSLFR