2.A.1.14.50 MFS carrier, a putative drug exporter of 450 aas and 12 TMSs in a 6 + 6 TMS arrangement. It exports polymyxin B, CCCP and verapamil (Gao et al. 2023).
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Accession Number: | WP_081255865.1 |
Protein Name: | WP_081255865.1 MFS transporter [Pandoraea pnomenusa] |
Length: | 451 |
Molecular Weight: | |
Species: | Pandoraea pnomenusa [93220] |
Number of TMSs: | 12 |
Substrate |
polymyxin B1, verapamil |
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1: MKPSESSASA PRASANAGVE RATIHHITWR LVPLIFIAWF VNYLDRANIG FAALQMNQEL
61: GMGPEMFGFA AGIFYLGYIG FEVPSNMMMH RFGARVWLAR IMITWGIVSA GTAFVQTPQQ
121: LYVARLLLGV VEAGFFPSVL YYLATWFPKQ HLGRAISRVY SANIFSLIVG APVSALLIDH
181: FHEASGFSGW RWMMMIEGLP AVALGVIAWF VLVDRPSDAK WLSPAQREWL VTTMANEEAV
241: AATTGTSSFR SAMVAPMVWL MGLLYFCIGI GFFGISTWLP QVIRQMSRLS IVEIGLVSAI
301: PFILGAIAMF ANARHSDRTM ERRWHLAGAL FVGAAGLAGS GLTSTLPIVS FVCICVAAAG
361: IVGSLSVFWT IPPTFLSGAG AAGGIALINA ISGLAGFFAP WLVGVARGHS TDFTLALYCL
421: AASAAAAAVL AAVLPYGKRK PRDEVSAYAH