2.A.1.2.87
Purine efflux porter of 392 aas, CepA. Exports purine analogues, 6-mercaptopurine and 6-mercaptoguanine, but not to
2-aminopurine and purine nucleoside analogues. May show increased resistance to the antibiotics nalidixic acid and
ampicillin (Sim et al. 2014).
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| Accession Number: | Q8NLD6 |
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| Protein Name: | Arabinose efflux permease |
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| Length: | 392 |
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| Molecular Weight: | 40745.00 |
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| Species: | Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) [196627] |
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| Number of TMSs: | 12 |
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| Substrate |
purines, ampicillin, nalidixic acid, tioguanine, mercaptopurine |
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1: MSTTTAPEAR FPVVPLTAMS FAAFVYVTFE MFAVGLIKPM ASDLGVSESS IGLLMTVYAT
61: VVAVVTIPAM LWVSRFNKRT VFLITLAFLA TGIVVQALTV NYGMLAIGRT IAALTHGVFW
121: ALVGPMAARM SPGHTGRAVG VVSIGSTMAL VVGSPLATWI GELIGWRPAT WILGALTIAA
181: VAVLIPTVPS LPPLPDTESE SKEKKSLPWG LISLVIFLLL AVTGVFAAYT YLGLIIAETA
241: GDSFVSIGLF AFGALGLIGV TVATRTVDQR MLRGSVHTTT LFVIAAILGQ IAFGLEGTLA
301: VVAIFLAVTV FGGAYGALPT LGTTIFLHAG RDHPDTASSI YVVTYQVGIA SGAALGAMAV
361: DADWVAGTLW IMAGLSLAST LALALWSRPL LK