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| Accession Number: | P42670 |
| Protein Name: | Pur8 |
| Length: | 503 |
| Molecular Weight: | 51852.00 |
| Species: | Streptomyces lipmanii (Streptomyces alboniger) [132473] |
| Number of TMSs: | 14 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | hydron, puromycin, puromycin |
Cross database links:
| Pfam: | PF07690 |
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Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0015520
F:tetracycline:hydrogen antiporter activity
GO:0017000
P:antibiotic biosynthetic process
GO:0046677
P:response to antibiotic
GO:0015904
P:tetracycline transport
GO:0055085
P:transmembrane transport
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References (1)[1] “The pur8 gene from the pur cluster of Streptomyces alboniger encodes a highly hydrophobic polypeptide which confers resistance to puromycin.” Tercero J.A.et.al. 7916693
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MARKPDISAV PVESAACQGP DPRRWWGLVV ILAAQLLVVL DGTVVNIALP SVQRDLGMSD 61: TSRQWVITAY TLAFGGLLLL GGRVADAFGR RRIFAVGILG FGLASLLGGA APDPGTLFLA 121: RALQGVFAAA LAPAALALIN TLFTEPGERG KAFGVYGAVS GGGAAVGLLA GGLLTEYLDW 181: RWCLYVNAPV ALLALLGCRL LPRDRRTGRA VRLDLPGTLL GCGGLVAIVY AFAEAESGWG 241: DPLVVRLLVL GVLMLVAFAL VERRVQDPLL PPGVVAHRVR GGSFLVVGLP QIGLFGLFLF 301: LTYYLQGILD YSPVLTGVAF LPLGLGIAVG SSLIAARLLP RTRPRTLIVG ALLAAAAGMA 361: LLTRLEPDTP QVYLTHLLPA QILIGLGIGC MMMPAMHTAT ARVAPHEAGA AAAVVNSAQQ 421: VGGALGVALL NTVSTGATAA YLADHGTSPA ATVDGTVHGY TVAIAFAVGV LLLTAVLAWV 481: LIDSRTEAAD ETGSASVTPA RPR