2.A.1.3.47 The trichothecene efflux pump, TRI12 (Alexander et al., 1999; Wuchiyama et al., 2000). Trichothecenes are plant growth promoters and bio-control agents (See also Fang et al. (2012)). TRI12 secretes toxic trichothecene compounds like T-2 toxin, nivalenol and deoxynivalenol.
|
Accession Number: | Q9C1B3 |
Protein Name: | Trichothecene efflux pump |
Length: | 598 |
Molecular Weight: | 64617.00 |
Species: | Fusarium sporotrichioides [5514] |
Number of TMSs: | 13 |
Substrate |
trichothecene |
---|
Pfam: |
PF06609
|
[1] “The TRI11 gene of Fusarium sporotrichioides encodes a cytochrome P-450 monooxygenase required for C-15 hydroxylation in trichothecene biosynthesis.” Alexander N.J. et.al. 9435078
[2] “A genetic and biochemical approach to study trichothecene diversity in Fusarium sporotrichioides and Fusarium graminearum.” Brown D.W. et.al. 11352533
[3] “Fusarium Tri8 encodes a trichothecene C-3 esterase.” McCormick S.P. et.al. 12039755
|
1: MTVVVPEEGL DLESQPDDRM RAKALATSAA ELPDGYYRSP RIVASFAAFS MNVVATYFVL
61: QASASALPNI LQDVGQSENS SLFSTLWTTG QAVSILMMGR LTDRFGRRPF VILTHILGLV
121: GAIVGCTATK FNTLLAAMTM LGVAAGPAGA SPLFIGELMS NKTKFLGLLI VSAPVVATNG
181: LSPYLGQRLA IQGSWRWIFY IYIIMSTIAV TLIIIWYYPP SFAQLHGKKV SKREELAKVD
241: WIGIILVIAG TSLFLLGVSW GGQPNNPWNS AKVIGLISSG AGTLVIFALY EVYGKPERPM
301: VPPSLFKDTR GFVCILIISS IMGSMHLSLV IMYPQQVVNI FGSSLKNWEE TAWMSATASF
361: GTGAGVVVLG SLFHLVRHIR WQILVGAMWL TAFLGAMSSI NRDNKNSAIA LSVMTGFVVA
421: WAQDITMLLV QFITTDENLG VAFAVVAAAR PFAGSIFTAA FISVYTNRYP RELATHLSSA
481: LRGTGFPQGS FSSLLEAAKS GRMEAVNALP GMTTEISSVV SQAMADSYTA SYANVYYFAM
541: ALGVIPIIAS LCMRDLDCYL TDHVPHQLYD RKNAHKDVLE GNSESQPSPI ILSMADKE