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| Accession Number: | P71879 |
| Protein Name: | Multidrug resistance protein stp |
| Length: | 537 |
| Molecular Weight: | 57115.00 |
| Species: | Mycobacterium tuberculosis [1773] |
| Number of TMSs: | 15 |
| Location1 / Topology2 / Orientation3: | Cell membrane1 / Multi-pass membrane protein2 |
| Substrate | tetracycline, drug, spectinomycin |
Cross database links:
| Entrez Gene ID: | 887274 924017 |
|---|---|
| Pfam: | PF07690 |
| KEGG: | mtc:MT2395 mtu:Rv2333c |
Gene Ontology
GO:0016021
C:integral to membrane
GO:0005886
C:plasma membrane
GO:0046677
P:response to antibiotic
GO:0055085
P:transmembrane transport
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References (3)[1] “Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.” Cole S.T.et.al. 9634230 [2] “Whole-genome comparison of Mycobacterium tuberculosis clinical and laboratory strains.” Fleischmann R.D.et.al. 12218036 [3] “Contribution of the Rv2333c efflux pump (the Stp protein) from Mycobacterium tuberculosis to intrinsic antibiotic resistance in Mycobacterium bovis BCG.” Ramon-Garcia S.et.al. 17242035
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External Searches:
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Analyze:
| Predict TMSs (Predict number of transmembrane segments) | ||||
| FASTA formatted sequence |
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1: MNRTQLLTLI ATGLGLFMIF LDALIVNVAL PDIQRSFAVG EDGLQWVVAS YSLGMAVFIM 61: SAATLADLDG RRRWYLIGVS LFTLGSIACG LAPSIAVLTT ARGAQGLGAA AVSVTSLALV 121: SAAFPEAKEK ARAIGIWTAI ASIGTTTGPT LGGLLVDQWG WRSIFYVNLP MGALVLFLTL 181: CYVEESCNER ARRFDLSGQL LFIVAVGALV YAVIEGPQIG WTSVQTIVML WTAAVGCALF 241: VWLERRSSNP MMDLTLFRDT SYALAIATIC TVFFAVYGML LLTTQFLQNV RGYTPSVTGL 301: MILPFSAAVA IVSPLVGHLV GRIGARVPIL AGLCMLMLGL LMLIFSEHRS SALVLVGLGL 361: CGSGVALCLT PITTVAMTAV PAERAGMASG IMSAQRAIGS TIGFAVLGSV LAAWLSATLE 421: PHLERAVPDP VQRHVLAEII IDSANPRAHV GGIVPRRHIE HRDPVAIAEE DFIEGIRVAL 481: LVATATLAVV FLAGWRWFPR DVHTAGSDLS ERLPTAMTVE CAVSHMPGAT WCRLWPA